What is CAS # 39771-34-1
4-Amino-2,6-dibromopyridine (CAS#39771-34-1) is a chemical compound that belongs to the pyridine family. It is a pale yellow crystalline solid that is soluble in water and organic solvents. This compound is widely used in the pharmaceutical and agrochemical industries due to its diverse biological activities. In this article, we will discuss the synthesis, properties, and applications of 4-Amino-2,6-dibromopyridine.
The synthesis of 4-Amino-2,6-dibromopyridine involves the reaction of 4-bromo-2,6-dichloropyridine with ammonia in the presence of a palladium catalyst. The reaction takes place at high temperature and pressure, and the product is obtained in good yield. Alternatively, the compound can also be prepared by reacting 4-amino-2,6-dichloropyridine with hydrobromic acid in the presence of a reducing agent such as zinc or iron. The synthesis of this compound is relatively straightforward, and it can be easily scaled up for industrial production.
39771-34-1 Properties and Applications
4-Amino-2,6-dibromopyridine has a wide range of biological activities, including antifungal, antibacterial, and anticancer properties. It has been found to be effective against various fungal and bacterial strains, including Candida albicans, Escherichia coli, and Staphylococcus aureus. In addition, this compound has shown promising results in inhibiting the growth of cancer cells, making it a potential candidate for anticancer drug development.
4-Amino-2,6-dibromopyridine is also used as a building block in the synthesis of other pharmaceutical and agrochemical compounds. It can be used to prepare various pyridine derivatives, which have diverse biological activities. For example, it can be used to synthesize 4-Amino-2,6-dibromo-3-nitropyridine, which has been found to be effective against the growth of malaria parasites. It can also be used to prepare herbicides and insecticides, which are widely used in agriculture.
39771-34-1 Safety and Handling
4-Amino-2,6-dibromopyridine is a hazardous chemical and should be handled with care. It is toxic if ingested or inhaled and can cause skin and eye irritation. Proper safety measures should be taken when handling this compound, including the use of personal protective equipment such as gloves, goggles, and a respirator. It should be stored in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.
In conclusion, 4-Amino-2,6-dibromopyridine is a versatile compound with diverse biological activities. Its synthesis is relatively straightforward, and it has numerous applications in the pharmaceutical and agrochemical industries. However, it should be handled with care due to its hazardous nature.
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