What is CAS#433711-95-6
The chemical compound (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester, also known as CAS#433711-95-6, is a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. This compound is widely used in the chemical industry due to its unique properties and versatile applications. In this article, we will discuss the synthesis, properties, and applications of (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester in detail.
CAS#433711-95-6 Synthesis of (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester
The synthesis of (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester involves the reaction of pyridine with tert-butyl chloroformate and sodium bromide. The reaction is carried out in the presence of a suitable solvent such as dichloromethane or acetonitrile. The reaction mixture is then stirred at room temperature for several hours to allow the reaction to proceed to completion. After the reaction is complete, the solvent is removed, and the crude product is purified by column chromatography to obtain the final product. The yield of the product is typically high, and the purity is also excellent.
CAS#433711-95-6 Properties and Applications of (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester
1. Properties: (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester is a white to off-white crystalline solid with a melting point of 94-97°C. The compound is sparingly soluble in water but soluble in most organic solvents such as methanol, ethanol, and acetone. The compound is stable under normal conditions and does not decompose easily.
2. Applications: (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester is a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound is used in the synthesis of anti-inflammatory drugs, anti-cancer drugs, and anti-viral drugs. The compound is also used in the synthesis of insecticides and herbicides. The compound is widely used in the chemical industry due to its unique properties and versatile applications.
3. Toxicity: (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester is a relatively safe compound with low toxicity. The compound is not classified as a hazardous substance by any regulatory authority. However, as with any chemical, proper handling and storage procedures should be followed to avoid any potential hazards.
(2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester is a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound is widely used in the chemical industry due to its unique properties and versatile applications. The synthesis of the compound is relatively simple and yields a high purity product. The compound is relatively safe and not classified as a hazardous substance. As the demand for pharmaceuticals and agrochemicals continues to grow, the importance of (2-Bromo-pyridin-4-yl)carbamic acid tert-butyl ester in the chemical industry will only continue to increase.
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