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methotrexate
Chemical Blogs
user001

Synthesis of impurities in methotrexate

Synthesis of impurities in methotrexate Synthesis of impurities in methotrexate Objective: To synthesize three major impurities in it API. Methods: The impurity E was synthesized by cyclization of p-acid,tetraaminopyrimidine The impurity E was synthesized by cyclization, impurity D was synthesized by hydrolysis, and impurity C was obtained by hydrolysis of methotrexate. The structures of the

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methotrexate
Chemical Blogs
user001

Synthesis process of methotrexate

Synthesis process of methotrexate Abstract methotrexate methotrexate(1), chemically known as N-(4-(((2,4-diamino-6-pyridinyl)methyl)methylamino)benzoyl)-L-glutamate is a widely used antitumor drug in the field of cancer chemotherapy.111 Especially after the clinical adoption of high-dose it therapy in the past 20 years and its approval by the U.S. FDA for the treatment of rheumatoid arthritis in 1988,3 the demand for

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isopropanol
Chemical Blogs
user001

Production process and application of isopropanol happy

Production process and application of isopropanol Production process and application of isopropanol Abstract It is a widely used organic solvent and raw material. The manufacturing technology of isopropanol was introduced. The economics of acetone hydrogenation and propylene hydration were compared. The application prospect of isopropanol was also analyzed. It is    considered that the route of

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p-xylene
Chemical Blogs
user001

Global p-xylene supply and demand

Global p-xylene supply and demand Global p-xylene supply and demand Abstract: The capacity of global it has been steadily increasing in recent years, and the new capacity mainly comes from the Chinese mainland, Vietnam, India, South Korea, and Saudi Arabia in the Middle East. In 2020, the global production capacity of it was 64.476 million

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Acrylonitrile
Chemical Blogs
user001

Acrylonitrile Production and Market

Acrylonitrile Production and Market​ Acrylonitrile Production and Market (Research Institute of Jilin Petrochemical Company, PetroChina, Jilin 132021 China) Abstract: The paper summarizes acrylonitrile production capacity, actual output, market demand and price both at home and abroad, analyzes the actuality and development trend of acrylonitrile plants, introduces acrylonitrile research & development and technology progress and puts

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Methotrexate CAS# 59-05-2
Chemical Blogs
Peter Ni

The synthesis process of methotrexate

The synthesis process of methotrexate Abstract An overview of the progress of the main synthetic methods of methotrexate and the preparation of key intermediates is given. Keywords Methotrexate, synthesis Methotrexate(1),chemically known as N-(4-(((2,4-diamino-6-phthalimide)methyl)methylamino)benzoyl)-L-glutamate is a widely used antitumor drug in the field of cancer chemotherapy.111, Especially after the clinical adoption of high-dose methotrexate therapy in the

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ABS Resin Production and Market

The paper summarizes ABS resin production capacity, actual output, market demand and price both at home and abroad, analyzes the actuality and development trend of ABS Resin plants, and introduces ABS resin research & development and technology progress.

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What is benzalkonium chloride?

This new coronary epidemic makes people gradually have a deeper understanding of protection and disinfection, all countries are looking for better disinfectants to deal with this epidemic, one of the products is benzalkonium chloride for this epidemic disinfection effect is very good, do you know benzalkonium chloride? Benzalkonium chloride is a cationic surfactant, which is

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What is scale inhibitor?

Scale inhibitor in our daily industrial production process of water purification has a vital role, but do you understand what is scale inhibitor? Scale inhibitor is a water treatment agent, is a water treatment agent used in industrial cooling circulating water, in order to prevent the evaporation of water in the industrial cycle process caused

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What water treatment agents are used for the swimming pool?

When summer comes, swimming becomes an essential sport, but how to keep the pool hygienic also becomes an important job. A lot of customers are asking me what kinds of water treatment chemicals are used for swimming pools so that they can import them from China for local distribution and be able to make a

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