2,2,6,6-Tetramethylpiperidinooxy CAS# 2564-83-2

2,2,6,6-Tetramethylpiperidinooxy, Promotion Season Now in Store and Free Sample for Testing with Factory Price
  • Appearance:Red brown flat crystal
  • Assay: 98.5%min
  • Packaging: 25kg/drum
  • Sample: Available

Quality Control of 2,2,6,6-Tetramethylpiperidinooxy

Chemical Structure
2,2,6,6-Tetramethylpiperidinooxy CAS# 2564-83-2
Packing of 2,2,6,6-Tetramethylpiperidinooxy

Description of 2,2,6,6-Tetramethylpiperidinooxy

(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl or (2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl, commonly known as TEMPO, is a chemical compound with the formula (CH2)3(CMe2)2NO. This heterocyclic compound is a red-orange, sublimable solid. As a stable radical, it has applications in chemistry and biochemistry. TEMPO was discovered by Lebedev and Kazarnowskii in 1960. It is prepared by oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO is widely used as a radical marker, as a structural probe for biological systems in conjunction with electron spin resonance spectroscopy, as a reagent in organic synthesis, and as a mediator in controlled radical polymerization. The stability of this radical is attributed to the resonance provided by non-bonding electrons on the nitrogen atom, which form a 2c3e (half-) bond between nitrogen and oxygen, and hyperconjugative ability. Additional stability arises from the steric protection provided by the four methyl groups adjacent to the nitroxyl group; however, the methyl groups prevent a double bond occurring between either carbon adjacent to nitrogen. The stability of the radical is also indicated by the weakness of the O–H bond in the hydrogenated derivative TEMPO–H. With an O–H bond dissociation energy of about 70kcal/mol, this bond is about 30% weaker than a typical O–H bond.

Basic Info of 2,2,6,6-Tetramethylpiperidinooxy

Basic Info

Chemical Name



free radical,2,2,6,6-Tetramethylpiperidine 1-oxyl;

2,2,6,6-Tetramethyl-1-piperidinyloxy;2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical;2,2,6,6-Tetramethylpiperidinooxy;





Molecular Formula


Molecular Weight






Safety Info



Hazard Class


Safety Statements


HS Code


WGK Germany


Packing Group



UN 3263

Risk Statements

R34; R36/37/38

Hazard Codes

C; Xi

Hazard Declaration


Signal Word


Caution Statement

P280; P305 + P351 + P338; P310





Appearance & Physical State

orange crystals or powder


1 g/cm3

Boiling Point


Melting Point


Flash Point



Stable. Incompatible with strong acids, strong oxidizing agents. Refrigerate.

Storage Condition



Numbering system

PubChem number


BRN number


MDL number


RTECS number


EINECS number


PubChem number



Share on facebook
Share on twitter
Share on linkedin

What is 2,2,6,6-Tetramethylpiperidinooxy?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 2,2,6,6-Tetramethylpiperidinooxy which has developed particularly rapidly in recent years. Do you know about 2,2,6,6-Tetramethylpiperidinooxy?


The official answer:2,2,6,6-Tetramethylpiperidine oxide, an organic chemical substance, molecular formula: C9H18NO.

What’s the application of 2,2,6,6-Tetramethylpiperidinooxy?

TEMPO has wider applications in chemistry, biology, food industry, agriculture, and other fields. It has the functions of trapping free radicals, bursting single-linear oxygen, and selective oxidation. In polymer chemistry, it is used as a radical trapping agent, polymerization inhibitor, anti-aging agent, thermal degradation inhibitor, and light and heat stabilizer, and it can also combine with reactive chain radicals to form covalent dormant species. The covalent dormant species can be cleaved into chain radicals and grow again. TEMPO/NaClO/NaBr is a recyclable oxidation system in which the real oxidant is the NaClO oxidation of TEMPO to produce the intermediate N- oxoammonium ion, the primary hydroxyl nucleophile attacks the ion, the hydroxyl group is oxidized to a carboxyl group, and the ion is converted to hydroxylamine, which is then oxidized to N-oxoammonium ion by the co-oxidant, and so on. Many other oxidation systems are containing TEMPO.


Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

CEO Email: inquiry@sincerechemical.com

CEO Phone Number:
+86-188-6575 9396

CEO WhatsApp:
+86-188-6575 9396

Request A Free Quote

Keywords of 2,2,6,6-Tetramethylpiperidinooxy

2,2,6,6-Tetramethylpiperidinooxy ,2564-83-2, buy 2,2,6,6-Tetramethylpiperidinooxy , 2,2,6,6-Tetramethylpiperidinooxy  supplier, purchase 2,2,6,6-Tetramethylpiperidinooxy , 2,2,6,6-Tetramethylpiperidinooxy  cost, 2,2,6,6-Tetramethylpiperidinooxy  manufacturer, order 2,2,6,6-Tetramethylpiperidinooxy , high purity 2,2,6,6-Tetramethylpiperidinooxy


United Kingdom Giles
United Kingdom Giles
Read More
Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
Read More
In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
Read More
Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
USA Franklin
USA Franklin
Read More
Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
Canada Kate
Read More
I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
Read More
Sincere Chemical is a reliable and professional company. Not only on exporting but also their professional team service. Their team gave us so many suggestions for our new project. We are really satisfied with their awesome service and best product quality. Sincere-Chem’s vendor code is 51465768 in our cooperated vendor list system.
Read More
I have visited Sincere Chemical company in the year 2018. Their company can be considered as one of the most professional, customer-focused, and product quality-driven companies that I have worked with in recent years.
Brazil Aline
Brazil Aline
Read More
We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
Mexico Gonzalo
Read More
Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...