3-Hydroxy-1-AdaMantane Carboxylic Acid CAS# 42711-75-1
3-Hydroxy-1-AdaMantane Carboxylic Acid, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Appearance: White or off-white crystalline powder.
- Assay: 98.5%min.
- Packaging: 25kg/cardboard drum.
- Sample: Available.
3-Hydroxy-1-AdaMantane Carboxylic Acid: The Complete Guide
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Description of 3-Hydroxy-1-AdaMantane Carboxylic Acid
1-Carboxy-3-adamantane is used in the synthesis of potent pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 which could be applied to the treatment of ulcers or in hormone therapy treatments relating to cortisol.
Basic Info of 3-Hydroxy-1-AdaMantane Carboxylic Acid
3-hydroxyadamantane-1-carboxylic acid;3-Hydroxy-1-adamantane carboxylic Acid;3-Hydroxy-1-Adamantane Carboxylic Acid;1-Hydroxy-3-Adamantane Carboxylic Acid;
357.2ºC at 760 mmHg
What is 3-Hydroxy-1-AdaMantane Carboxylic Acid?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 3-Hydroxy-1-AdaMantane Carboxylic Acid which has developed particularly rapidly in recent years. Do you know about 3-Hydroxy-1-AdaMantane Carboxylic Acid?
The official answer:3-Hydroxy-1-adamantane carboxylic acid is a chemical compound with a molecular weight of 196.14.
What’s the application of 3-Hydroxy-1-AdaMantane Carboxylic Acid?
Used in the synthesis of adamantane derivatives and adalbene. 1-Adamantaneacetic acid can be obtained by reaction with vinylidene chloride. 1-Adamantaneacetic acid is then brominated and hydrolyzed to 3-hydroxy-1-adamantane acetic acid, and 1,3-adamantane acetic acid can be obtained by reaction with vinylidene chloride.
1-Adamantanol and acetanilide undergo Fucetylation reaction at room temperature in 98% sulfuric acid medium, which can directly synthesize 1,3-bis(4-acetaminophen)adamantane, and synthesize 1,3-bis(4-anilino)adamantane from its alkali hydrolysis. This synthetic route has the advantages of higher reaction yield and easy purification, which largely facilitates the synthesis of 1,3-adamantane diaryl derivatives.
1-Adamantanol, 4-bromophenol was used as the raw material to make adapalene, and the 2-1-Adamantane-4-bromophenol product was catalyzed by concentrated sulfuric acid; then methylated with dimethyl sulfate to obtain 2-1-Adamantane-4-bromophenyl ether, and the Grignardized product of this bromophenyl ether was then reacted with methyl 6-Bromo-2-naphthoic acid to produce 6-3-1-Adamantane-4-methoxyphenyl-2-naphthoic acid methyl naphthalene-2-carboxylate. The product was saponified in the presence of sodium hydroxide to hydrolyze the adapalene.
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