4-Dimethylaminopyridine CAS# 1122-58-3
4-Dimethylaminopyridine, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Appearance: White powder
- Assay: 99. 0%min
- Packaging: 25kg/ Cardboard drums
- Sample: Available





4-Dimethylaminopyridine: The Complete Guide
- Chapter 1: Quality Control of 4-Dimethylaminopyridine
- Chapter 2: Description of 4-Dimethylaminopyridine
- Chapter 3: Basic Info of 4-Dimethylaminopyridine
- Chapter 4: What is 4-Dimethylaminopyridine?
- Chapter 5: What’s the application of 4-Dimethylaminopyridine?
- Chapter 6: Keywords of 4-Dimethylaminopyridine
- Chapter 7:WHY THEY SAY TO US
- Chapter 8: Hot Sale Products
Request A Free Quote
Quality Control of 4-Dimethylaminopyridine
Quality Control & MSDS
Chemical Structure

Packing of 4-Dimethylaminopyridine


Description of 4-Dimethylaminopyridine
4-Dimethylaminopyridine (DMAP) is a derivative of pyridine with the chemical formula (CH3)2NC5H4N. This colourless solid is of interest because it is more basic than pyridine, owing to the resonance stabilisation from the NMe2 substituent.
Because of its basicity, DMAP is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. Chiral DMAP analogues are used in kinetic resolution experiments of mainly secondary alcohols and Evans auxiliary type amides.
Basic Info of 4-Dimethylaminopyridine
Basic Info
Chemical Name | 4-Dimethylaminopyridine |
Synonyms | 4-Dimethylaminopyrid;AURORA KA-6495;N-(4-Pyridyl)dimethylamine;4-Pyridinamine, N,N-dimethyl-;4-Dimethylaminepyridine;Expand |
CAS No. | 1122-58-3 |
Molecular Formula | C7H10N2 |
Molecular Weight | 122.16800 |
PSA | 16.13000 |
LogP | 1.14760 |
Safety Info
RTECS | US8400000 |
Hazard Class | 8 |
Safety Statements | S26-S28-S36/37/39-S45 |
HS Code | 2933399090 |
WGK Germany | 3 |
Packing Group | II |
RIDADR | UN 1760/2811 |
Risk Statements | R24/25; R34 |
Hazard Codes | T |
Hazard Declaration | H302; H311; H315; H319; H335; H351 |
Signal Word | Danger |
Caution Statement | P280; P301 + P312 + P330; P302 + P352 + P312; P304 + P340 + P312; P305 + P351 + P338; P337 + P313 |
Symbol | GHS06, GHS08 |
Properties
Appearance & Physical State | white to yellow crystalline powder |
Density | 1.012 g/cm3 |
Boiling Point | 162ºC (50 mmHg) |
Melting Point | 108-113ºC |
Flash Point | 110ºC |
Refractive Index | n20/D 1.431 |
Water Solubility | 76 g/L (25 ºC) |
Stability | Stable. Incompatible with acids, oxidizing agents. |
Storage Condition | Store in dark |
Vapor Pressure | 0.431mmHg at 25°C |
Numbering system
MDL number | MFCD00006418 |
EINECS number | 214-353-5 |
RTECS number | US9230000 |
BRN number | 110354 |
What is 4-Dimethylaminopyridine?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 4-Dimethylaminopyridine which has developed particularly rapidly in recent years. Do you know about 4-Dimethylaminopyridine?
The official answer:4-Dimethylaminopyridine is a new high-efficiency catalyst widely used in chemical synthesis. 4-Dimethylaminopyridine is a new high-efficiency catalyst widely used in chemical synthesis in recent years, and the resonance of the electron-donating dimethylamine with the parent ring (pyridine ring) on its structure can strongly activate the nucleophilic substitution of the nitrogen atom on the ring, which significantly catalyzes the acylation (phosphorylation, sulfonylation, carbonylation) reaction of high potential resistance and low reactivity alcohols and amines, and its activity is about 104-6 times that of pyridine.
What’s the application of 4-Dimethylaminopyridine?
4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. The resonance of the electron-donating dimethylamine with the parent ring (pyridine ring) on its structure can strongly activate the nucleophilic substitution of the nitrogen atom on the ring and significantly catalyze the acylation (phosphorylation, sulfonylation, carbonylation) reactions of high potential resistance and low reactivity of alcohols and amines, and its activity is about 104-6 times that of pyridine. It has high catalytic ability in various types of reactions such as acylation, alkylation, etherification, esterification, and ester exchange in organic synthesis, drug synthesis, pesticides, pharmaceuticals, dyes, fragrances, polymer chemistry, and analytical chemistry, and has an extremely obvious effect on improving yields. Its advantages are: the catalyst dosage is small, usually only 0.01-5% of the molarity of the reaction substrate can be, the acid produced by the reaction can be neutralized by organic or inorganic bases; mild reaction conditions, generally at room temperature can be carried out, saving energy; wide choice of solvent, in polar, non-polar organic solvents can be carried out; short reaction time, using pyridine for a long time, while the DMAP is a few minutes to complete the reaction, thus greatly improving labor productivity; high yield, such as pyridine almost does not react with the hydroxyl compounds with large spatial resistance, the use of DMAP yield up to 80-90%, which can improve the reaction yield and product quality and simplify the process; fewer side reactions, small odor, less waste; due to the excellent catalytic performance of DMAP, known as “super catalyst “It has become one of the most commonly used catalysts for organic synthesis workers.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.
Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.
CEO Email: inquiry@sincerechemical.com
CEO Phone Number:
+86-188-6575 9396
CEO WhatsApp:
+86-188-6575 9396
Request A Free Quote
Keywords of 4-Dimethylaminopyridine
4-Dimethylaminopyridine, 1122-58-3, buy 4-Dimethylaminopyridine, 4-Dimethylaminopyridine supplier, purchase 4-Dimethylaminopyridine, 4-Dimethylaminopyridine cost, 4-Dimethylaminopyridine manufacturer, order 4-Dimethylaminopyridine, high purity 4-Dimethylaminopyridine.
WHY THEY SAY TO US








