Bronopol CAS# 52-51-7
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- Appearance: White or almost white crystal powder
- Assay: 99. 0%min
- Packaging: 25kg/fiber drum
- Sample: Available
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Quality Control of Bronopol
Quality Control & MSDS
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Description of Bronopol
Bronopol (INN) is an organic compound that is used as an antimicrobial. It is a white solid although commercial samples appear yellow.
Bronopol was invented by The Boots Company PLC in the early 1960s and first applications were as a preservative for pharmaceuticals. Owing to its low mammalian toxicity (at in-use levels) and high activity against bacteria (especially the troublesome Gram-negative species), bronopol became popular as a preservative in many consumer products such as shampoos and cosmetics. It was subsequently adopted as an antimicrobial in other industrial environments such as paper mills, oil exploration and production facilities, as well as cooling water disinfection plants.
Basic Info of Bronopol
R21/22; R37/38; R41; R50
Appearance & Physical State
White to slightly yellow crystals or crystalline powder
358ºC at 760 mmHg
25 g/100 mL (22 ºC)
Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
What is Bronopol?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Bronopol which has developed particularly rapidly in recent years. Do you know about Bronopol?
The official answer: Bronopol, chemical name 2-Bromo-2-nitro-1,3-propanediol, other names are bronopol, inhibition alcohol, etc… Foreign trade name: Bronopol, white crystalline powder, melting point: 122-130℃, very soluble in water, ethanol, propylene glycol, ethyl acetate, etc., slightly soluble in oil, insoluble in chloroform, acetone, etc. In 1919, made by E. Schmidt and R. Wilkendorf, since then, the British Pharmacy Association announced its generic name Bronopol. In 1970, it was patented in the UK for agricultural use.
What’s the application of Bronopol?
Bronopol is effective against a wide range of plant pathogenic bacteria and is mainly used as a seed treatment agent, etc. In addition, because of its broad-spectrum antibacterial properties, it was used as a disinfectant in medicine in the 1960s. With the increasing development of cosmetics and the broad-spectrum antimicrobial properties and good water solubility of bramble, it was used as a cosmetic preservative and developed extremely fast in the late 1980s. In recent years, Bronopol has been widely used in feed, paint, fur antiseptic, air conditioning circulating water antibacterial, oil field water injection antibacterial and aircraft, car and boat disinfection, etc., and the demand is rapidly increasing.
As a Bromo-nitro alcohol broad-spectrum antimicrobial agent, Bropol has the following characteristics: It has a spectrum of antimicrobial activity, and has effective antimicrobial activity in emulsion products containing surfactants in the range of pH 4 to 9, as well as in formulations with high concentrations of protein substances, especially for Pseudomonas Aeruginosa with strong antimicrobial activity; non-toxic, non-irritating and non-allergenic, the preservative in cosmetics The use amount is 0.01%～005%, and the toxicity test results show that the preservative is safe and is one of the cosmetic preservatives approved for use by the U.S. FDA; it has a synergistic effect in compounding. According to the U.S. FDA, the frequency of use of Bropol ranks among all preservatives used in cosmetics. It is the dramatic increase in commercial demand that has promoted the research and industrial production of Brompol.
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