Bronopol CAS# 52-51-7

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  • Appearance: White or almost white crystal powder
  • Assay: 99. 0%min
  • Packaging: 25kg/fiber drum
  • Sample: Available

Quality Control of Bronopol

Chemical Structure
Bronopol CAS# 52-51-7
Packing of Bronopol

Description of Bronopol

Bronopol (INN) is an organic compound that is used as an antimicrobial. It is a white solid although commercial samples appear yellow.

Bronopol was invented by The Boots Company PLC in the early 1960s and first applications were as a preservative for pharmaceuticals. Owing to its low mammalian toxicity (at in-use levels) and high activity against bacteria (especially the troublesome Gram-negative species), bronopol became popular as a preservative in many consumer products such as shampoos and cosmetics. It was subsequently adopted as an antimicrobial in other industrial environments such as paper mills, oil exploration and production facilities, as well as cooling water disinfection plants.

Basic Info of Bronopol

Basic Info

Chemical Name



2-Bromo-2-nitropropane-1,3-diol;BNPD;1,3-Propanediol, 2-bromo-2-nitro-;2-Bromo-2-nitro-1,3-propanediol;BNPK;



Molecular Formula


Molecular Weight






Safety Info



Hazard Class


Safety Statements


HS Code


Packing Group


WGK Germany



UN 3241

Risk Statements

R21/22; R37/38; R41; R50

Hazard Codes




Appearance & Physical State

White to slightly yellow crystals or crystalline powder


1.91 g/cm3

Boiling Point

358ºC at 760 mmHg

Melting Point


Flash Point


Refractive Index


Water Solubility

25 g/100 mL (22 ºC)


Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.

Storage Condition

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.

Numbering system




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What is Bronopol?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Bronopol which has developed particularly rapidly in recent years. Do you know about Bronopol?


The official answer: Bronopol, chemical name 2-Bromo-2-nitro-1,3-propanediol, other names are bronopol, inhibition alcohol, etc… Foreign trade name: Bronopol, white crystalline powder, melting point: 122-130℃, very soluble in water, ethanol, propylene glycol, ethyl acetate, etc., slightly soluble in oil, insoluble in chloroform, acetone, etc. In 1919, made by E. Schmidt and R. Wilkendorf, since then, the British Pharmacy Association announced its generic name Bronopol. In 1970, it was patented in the UK for agricultural use.

What’s the application of Bronopol?

Bronopol is effective against a wide range of plant pathogenic bacteria and is mainly used as a seed treatment agent, etc. In addition, because of its broad-spectrum antibacterial properties, it was used as a disinfectant in medicine in the 1960s. With the increasing development of cosmetics and the broad-spectrum antimicrobial properties and good water solubility of bramble, it was used as a cosmetic preservative and developed extremely fast in the late 1980s. In recent years, Bronopol has been widely used in feed, paint, fur antiseptic, air conditioning circulating water antibacterial, oil field water injection antibacterial and aircraft, car and boat disinfection, etc., and the demand is rapidly increasing.

As a Bromo-nitro alcohol broad-spectrum antimicrobial agent, Bropol has the following characteristics: It has a spectrum of antimicrobial activity, and has effective antimicrobial activity in emulsion products containing surfactants in the range of pH 4 to 9, as well as in formulations with high concentrations of protein substances, especially for Pseudomonas Aeruginosa with strong antimicrobial activity; non-toxic, non-irritating and non-allergenic, the preservative in cosmetics The use amount is 0.01%~005%, and the toxicity test results show that the preservative is safe and is one of the cosmetic preservatives approved for use by the U.S. FDA; it has a synergistic effect in compounding. According to the U.S. FDA, the frequency of use of Bropol ranks among all preservatives used in cosmetics. It is the dramatic increase in commercial demand that has promoted the research and industrial production of Brompol.


Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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United Kingdom Giles
United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
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Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
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USA Franklin
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Canada Kate
Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
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Brazil Aline
Brazil Aline
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Mexico Gonzalo
Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...