Diethyl malonate CAS# 105-53-3

Diethyl malonate, Promotion Season Now in Store and Free Sample for Testing with Factory Price
  • Appearance: Colorless transparent liquid
  • Assay: 99.5%min
  • Packaging: 200kg/ Plastic Drum.
  • Sample: Available

Quality Control of Diethyl malonate

Chemical Structure
Diethyl malonate CAS# 105-53-3
Packing of Bretazenil

Description of Diethyl malonate

Diethyl malonate, also known as DEM, is the diethyl ester of malonic acid. It occurs naturally in grapes and strawberries as a colourless liquid with an apple-like odour, and is used in perfumes. It is also used to synthesize other compounds such as barbiturates, artificial flavourings, vitamin B1, and vitamin B6.

Basic Info of Bretazenil

Basic Info

Chemical Name

Diethyl malonate


diethyl propanedioate;Malonic acid diethyl ester;Diethyl Malonate;Propanedioic acid, diethyl ester;Ethyl Malonate;



Molecular Formula


Molecular Weight







Safety Info



Safety Statements


HS Code


WGK Germany


Risk Statements


Hazard Codes




Appearance & Physical State




Boiling Point


Melting Point


Flash Point


Refractive Index



Stable. Combustible. Incompatible with strong oxidizing agents,

Storage Condition

Store in a cool, dry place. Keep container closed when not in use.

Vapor Density

5.52 (vs air)

Vapor Pressure

1 mm Hg ( 40 °C)


Numbering system

EINECS number


BRN number


MDL number


RTECS number



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What is Diethyl malonate?

Part I: Introduction

     With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Diethyl malonate which has developed particularly rapidly in recent years. Do you know about Diethyl malonate?


The official answer: Diethyl malonate is an organic substance with the chemical formula C7H12O4. Colorless aromatic liquid; melting point -50°C, boiling point 199.3°C; relative density 1.0551 (20/4°C); insoluble in water, easily soluble in alcohols, ethers, and other organic solvents.

What’s the application of Diethyl malonate

Use I】It is used as an intermediate of pharmaceutical weekly effect sulfonamide and barbiturate, and also as an intermediate of spice and dye.

Use 2] GB 2760 a 96 stipulates that it is allowed to be used as an edible flavor. Mainly used in the preparation of pears, apples, grapes, cherries, and other fruit-type flavors.

Use 3】Diethyl malonate is an important intermediate for the preparation of 2-amino-4,6-dimethoxypyrimidine and can be used to prepare sulfonylurea herbicides, such as bensulfuron, pyrimethanesulfuron, nicosulfuron, etc. It is also used as an intermediate for sulfonamide and barbiturate in medicine.

Use IV] Diethyl malonate is an intermediate of organic synthesis. Diethyl malonate is widely used in the production of dyes, fragrances, sulfonylurea herbicides, etc. Diethyl malonate is mainly used to produce ethoxymethoxylate, barbiturate, diethyl alkylmalonate, which is then used to synthesize pharmaceuticals such as norfloxacin, moxifloxacin, chloroquine, pautazone, etc. and synthetic dyes and pigments such as benzimidazolone organic pigments. Overseas diethyl malonate is mainly used to produce ethoxymethoxylate, barbiturate, and diethyl malonate alkylates.

【Use five】 Checking ammonia and potassium. Gas chromatography stationary solution (maximum use temperature 40 ℃, the solvent is benzene, chloroform, ethanol). Used as a solvent for resin and nitrocellulose, plasticizer. Organic synthesis.


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United Kingdom Giles
United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
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Korea Kim
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Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
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Brazil Aline
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Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...