Diethyl malonate CAS# 105-53-3
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- Appearance: Colorless transparent liquid
- Assay: 99.5%min
- Packaging: 200kg/ Plastic Drum.
- Sample: Available
Diethyl malonate: The Complete Guide
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Quality Control of Diethyl malonate
Quality Control & MSDS
Packing of Bretazenil
Description of Diethyl malonate
Diethyl malonate, also known as DEM, is the diethyl ester of malonic acid. It occurs naturally in grapes and strawberries as a colourless liquid with an apple-like odour, and is used in perfumes. It is also used to synthesize other compounds such as barbiturates, artificial flavourings, vitamin B1, and vitamin B6.
Basic Info of Bretazenil
diethyl propanedioate;Malonic acid diethyl ester;Diethyl Malonate;Propanedioic acid, diethyl ester;Ethyl Malonate;
Appearance & Physical State
Stable. Combustible. Incompatible with strong oxidizing agents,
Store in a cool, dry place. Keep container closed when not in use.
5.52 (vs air)
1 mm Hg ( 40 °C)
What is Diethyl malonate?
Part I: Introduction
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Diethyl malonate which has developed particularly rapidly in recent years. Do you know about Diethyl malonate?
The official answer: Diethyl malonate is an organic substance with the chemical formula C7H12O4. Colorless aromatic liquid; melting point -50°C, boiling point 199.3°C; relative density 1.0551 (20/4°C); insoluble in water, easily soluble in alcohols, ethers, and other organic solvents.
What’s the application of Diethyl malonate
Use I】It is used as an intermediate of pharmaceutical weekly effect sulfonamide and barbiturate, and also as an intermediate of spice and dye.
Use 2] GB 2760 a 96 stipulates that it is allowed to be used as an edible flavor. Mainly used in the preparation of pears, apples, grapes, cherries, and other fruit-type flavors.
Use 3】Diethyl malonate is an important intermediate for the preparation of 2-amino-4,6-dimethoxypyrimidine and can be used to prepare sulfonylurea herbicides, such as bensulfuron, pyrimethanesulfuron, nicosulfuron, etc. It is also used as an intermediate for sulfonamide and barbiturate in medicine.
Use IV] Diethyl malonate is an intermediate of organic synthesis. Diethyl malonate is widely used in the production of dyes, fragrances, sulfonylurea herbicides, etc. Diethyl malonate is mainly used to produce ethoxymethoxylate, barbiturate, diethyl alkylmalonate, which is then used to synthesize pharmaceuticals such as norfloxacin, moxifloxacin, chloroquine, pautazone, etc. and synthetic dyes and pigments such as benzimidazolone organic pigments. Overseas diethyl malonate is mainly used to produce ethoxymethoxylate, barbiturate, and diethyl malonate alkylates.
【Use five】 Checking ammonia and potassium. Gas chromatography stationary solution (maximum use temperature 40 ℃, the solvent is benzene, chloroform, ethanol). Used as a solvent for resin and nitrocellulose, plasticizer. Organic synthesis.
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