Guanidine thiocyanate CAS# 593-84-0

Guanidine thiocyanate can be used as a biochemical reagent, pharmaceutical intermediate. It is used for degreasing in the oil and grease industry, as a strong lipid degradation agent in the daily chemical industry, and cell membrane rupture agent in biopharmaceuticals. The principle of RNA extraction by guanidine isothiocyanate-phenol method: guanidine isothiocyanate and b-mercaptoethanol work together to inhibit the activity of RNase, while guanidine isothiocyanate and sodium dodecyl sarcosinate Chemicalbook work together to denature the protein, thus releasing RNA; under acidic conditions DNA rarely dissociates and is precipitated along with protein denaturation, while RNA is dissolved in the supernatant in the supernatant. Guanidine thiocyanate has been used:- to lyse colorectal adenocarcinoma cell lines before RNA isolation- as a PCR inhibitor for triple mitochondrial DNA (mtDNA) qPCR assaysGuanidine thiocyanate is a denaturant and is often Chemicalbook used for RNA isolation. It is used as a storage buffer for whole blood samples. Guanidine thiocyanate inactivates nucleases and is ideal for storing and freezing fecal samples for DNA studies. It is used in combination with phenol-chloroform in RNA extraction. Chemical depilatories are depilatories that soften the hair, reduce the strength of the hair, and wipe or rinse off the hair within 2-6 min. Because the composition of the hair stem is similar to the skin, chemical depilatories will inevitably damage the skin, so the depilatory agent is classified as a special purpose cosmetic. Thioglycolic acid type depilatory agent is the main depilatory agent nowadays, and it gradually replaces sulfide depilatory agent. These hair removal agents use hair removal active substances for thioglycolic acid and its salt, thioglycolic acid and its salt, thioglycolic Chemicalbook lactic acid, and it’s salt. From the performance and price considerations, the main use of thioglycolic acid and its salts for hair removal active agent. The application of some swelling agents (Swellingagents) helps to accelerate the speed of the hair removal action of mercapto compounds, thus, reducing the irritating effect on the skin. Such swelling agents include melamine, dicyandiamide, or a mixture of both (w = 0.5% to 2%), thiourea, potassium thiocyanate, guanidine thiocyanate, and PVP copolymer. They are mainly used in biopharmaceuticals, chemical reagents, etc. Inactivating agent (Chaotropic agent) and strong denaturing agent for denaturing lysis of cells; extraction of RNA and DNA.