Meglumine CAS# 6284-40-8
Meglumine, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Appearance: White crystal powder
- Assay: 99%min
- Packaging: 25kg/Drum
- Sample: Available
Meglumine: The Complete Guide
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Quality Control of Meglumine
Quality Control & MSDS
Chemical Structure
Packing of Bretazenil
Description of Meglumine
Meglumine is an amino sugar derived from glucose. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine, iothalamate meglumine and iodipamide meglumine.
Basic Info of Meglumine
Basic Info
Chemical Name | N-methylglucamine |
Synonyms | N-Methyl-D-glucamine;D-Glucitol, 1-deoxy-1-(methylamino)-;1-Deoxy-1-methylaminosorbitol; |
CAS No. | 6284-40-8 |
Molecular Formula | C7H17NO5 |
Molecular Weight | 195.21400 |
PSA | 113.18000 |
LogP | -2.96740 |
Safety Info
Safety Statements | S24/25 |
HS Code | 2922199090 |
Risk Statements | R36/37/38 |
Properties
Appearance & Physical State | white powder |
Density | 1.375 |
Boiling Point | 490.4ºCºC at 760 mmHg |
Melting Point | 128-132ºC |
Stability | Stable under normal temperatures and pressures. |
Storage Condition | Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. |
Numbering system
MDL number | MFCD00004707 |
What is Meglumine?
Part I: Introduction
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Meglumine which has developed particularly rapidly in recent years. Do you know about Meglumine?
The official answer: The selection of a suitable equilibrium ion for a drug by glucosamine is particularly important for improving the solubility and bioavailability of the drug. Glucosamine (N-methyl-D-glucosamine, MChemicalbookeglumine) is a widely used equilibrium ion for enhancing drug solubility. It is a sorbitol-derived amino sugar with a pKa value of 9.6.
What’s the application of Meglumine?
For diagnostic use as a co-solvent and surfactant for contrast agents.
Used in biochemical research.
Production method:It is obtained by condensation of glucose with monomethylamine followed by catalytic hydrogenation. Anhydrous ethanol and dry glucose are added to the reaction pot, and dry monomethylamine gas is passed at 50°C. After the reaction 1.Chemicalbook5-2h, the solution is gradually clarified and continues to be kept at 50°C for 2h to obtain glucose methylene amine condensation solution. Then it was added into the autoclave, pressurized to 2.5MPa by hydrogen in the presence of Reynolds nickel, and stirred at 80-85°C for 1-2h. Then it was discharged after cooling and releasing the pressure, and the upper layer of glucosamine ethanol solution was cooled and crystallized, filtered to obtain glucosamine crude product, and then refined to obtain the finished product.
Conclusion
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