Meglumine CAS# 6284-40-8

Meglumine, Promotion Season Now in Store and Free Sample for Testing with Factory Price
  • Appearance: White crystal powder
  • Assay: 99%min
  • Packaging: 25kg/Drum
  • Sample: Available

Quality Control of Meglumine

Chemical Structure
Packing of Bretazenil

Description of Meglumine

Meglumine is an amino sugar derived from glucose. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine, iothalamate meglumine and iodipamide meglumine.

Basic Info of Meglumine

Basic Info

Chemical Name

N-methylglucamine

Synonyms

N-Methyl-D-glucamine;D-Glucitol, 1-deoxy-1-(methylamino)-;1-Deoxy-1-methylaminosorbitol;

CAS No.

6284-40-8

Molecular Formula

C7H17NO5

Molecular Weight

195.21400

PSA

113.18000

LogP

-2.96740

Safety Info

Safety Statements

S24/25

HS Code

2922199090

Risk Statements

R36/37/38

 

Properties

Appearance & Physical State

white powder

Density

1.375

Boiling Point

490.4ºCºC at 760 mmHg

Melting Point

128-132ºC

Stability

Stable under normal temperatures and pressures.

Storage Condition

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water.

 

Numbering system

MDL number

MFCD00004707

 

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What is Meglumine?

Part I: Introduction

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Meglumine which has developed particularly rapidly in recent years. Do you know about Meglumine?

The official answer: The selection of a suitable equilibrium ion for a drug by glucosamine is particularly important for improving the solubility and bioavailability of the drug. Glucosamine (N-methyl-D-glucosamine, MChemicalbookeglumine) is a widely used equilibrium ion for enhancing drug solubility. It is a sorbitol-derived amino sugar with a pKa value of 9.6.

What’s the application of Meglumine?

For diagnostic use as a co-solvent and surfactant for contrast agents.

Used in biochemical research.

Production method:It is obtained by condensation of glucose with monomethylamine followed by catalytic hydrogenation. Anhydrous ethanol and dry glucose are added to the reaction pot, and dry monomethylamine gas is passed at 50°C. After the reaction 1.Chemicalbook5-2h, the solution is gradually clarified and continues to be kept at 50°C for 2h to obtain glucose methylene amine condensation solution. Then it was added into the autoclave, pressurized to 2.5MPa by hydrogen in the presence of Reynolds nickel, and stirred at 80-85°C for 1-2h. Then it was discharged after cooling and releasing the pressure, and the upper layer of glucosamine ethanol solution was cooled and crystallized, filtered to obtain glucosamine crude product, and then refined to obtain the finished product.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
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