Quercetin CAS# 117-39-5

Quercetin , Promotion Season Now in Store and Free Sample for Testing with Factory Price
  • Appearance: Fine Powder.
  • Assay: 98. 0%min
  • Packaging: 25kg/barrel.
  • Sample: Available

Quality Control of Quercetin

Chemical Structure
Packing of Quercetin

Description of Quercetin

Quercetin is a flavonol found in many fruits, vegetables, leaves and grains. It can be used as an ingredient in supplements, beverages, or foods.

Basic Info of Quercetin

Basic Info

Chemical Name






Molecular Formula


Molecular Weight







Safety Info



Hazard Class


Safety Statements


HS Code


Packing Group



UN 2811

Risk Statements

R25; R40

Hazard Codes


Hazard Declaration


Caution Statement

P301 + P310 + P330

Signal Word






Appearance & Physical State

Yellow to green yellow crystalline powde


1.799 g/cm3

Boiling Point

642.4ºCat 760 mmHg

Melting Point


Flash Point


Refractive Index



Stable under normal temperatures and pressures.

Storage Condition

Store at 0-5ºC

Vapor Pressure

9.03E-16mmHg at 25°C


Numbering system

RTECS number


BRN number


PubChem number


MDL number



Share on facebook
Share on twitter
Share on linkedin

What is Quercetin?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Quercetin which has developed particularly rapidly in recent years. Do you know about Quercetin?


The official answer: Quercetin, which is widely distributed in the plant world, is a flavonol compound with a variety of biological activities. Quercetin can fight free radicals, complex or capture free radicals to prevent lipid peroxidation in the body; it can directly inhibit tumors and effectively play a role in cancer prevention and anti-cancer; it also has strong biological activities in antibacterial, anti-inflammatory, anti-allergic, and preventing diabetic complications. In addition, quercetin also has the effects of lowering blood pressure, enhancing capillary resistance, reducing capillary fragility, lowering blood lipids, dilating coronary arteries, increasing coronary blood flow, etc. It also has auxiliary therapeutic effects on patients with coronary heart disease and hypertension. Quercetin is non-toxic, therefore, it is important for the treatment and prevention of cancer, aging, and cardiovascular diseases, and has a greater development value.

What’s the application of Quercetin?

Quercetin, a natural flavonoid widely found in nature, has gained intensive research and has been found to have multiple biological activities, such as antioxidant, antiviral, and anti-inflammatory effects, and can be used in cellular and animal experiments to treat liver, heart, spleen, lung, kidney, orthopedic diseases, and neurological disorders.

Antioxidant effect

Quercetin is a natural chelator that can chelate iron in the body, reduce iron overload in the body, and reduce oxidative damage caused by iron overload.  Quercetin has various effects such as antioxidant, scavenging free radicals, and inhibiting lipid peroxidation, which can antioxidant and protect cardiovascular health, and has shown better effects in anti-cancer. However, the data from such studies are from cytological experiments or animal experiments, and more validation is still needed to determine whether it works directly in humans.

Tumor-inhibiting activity

In terms of anti-cancer, quercetin has been shown in numerous studies to have inhibitory effects on various cancer cells. In terms of specific mechanisms of action, quercetin has a variety of biological effects, inhibiting a variety of enzymes involved in cell proliferation and signaling pathways in cancer cells.

On the other hand, it has also been shown that quercetin has some synergistic effects when used in combination with commonly used chemotherapeutic agents or radiotherapy, and has some promise for application. For example, quercetin can act in chemosensitization and radiosensitization chemotherapy also as an antiradiation, protecting normal cells from the side effects of chemotherapy and radiotherapy, and these advantages can significantly enhance its anticancer therapeutic effects. Various flavonols such as quercetin, kaempferol, and prunetinone have some preventive and curative effects against pancreatic cancer, especially for smokers, the effects may be more pronounced.

Quercetin may exert antitumor effects by inducing apoptosis in tumor cells. The expression of glucose transporter protein is significantly increased in primary liver cancer, and inhibition of its expression could be a new therapeutic direction for primary liver cancer. In the field of gastric cancer research, quercetin was likewise found to induce apoptosis and exert anti-tumor effects by triggering mitochondrial apoptosis-dependent growth inhibition, which could be a new target for the treatment of gastric cancer.

Mechanism of lipid-lowering and weight loss

Quercetin is a rich source of flavonoids in the diet, and studies have shown its lipid-lowering and weight-loss effects.

Quercetin can inhibit the decomposition of cholesterol esters into free cholesterol and can reduce the solubility of cholesterol in micellar solutions, inhibiting the absorption of cholesterol in the small intestine, which has the purpose of lowering lipids.

Quercetin is a potent regulator of plasma TG (triglyceride) levels.

Quercetin reduces intrahepatic lipid accumulation and decreases insulin resistance and NAFLD activity scores by regulating lipid metabolism gene expression, cytochrome P4502El (CYP2E1)-dependent lipid peroxidation, and associated lipotoxicity.

Quercetin has various effects such as inhibiting the proliferation of preadipocytes, inducing apoptosis of preadipocytes, and promoting lipolysis of mature adipocytes. And it can promote lipolysis metabolism and inhibit lipogenesis.

Quercetin can reduce the expression of IL-18, elevate the expression of IL-10, and alleviate the index abnormalities brought by a high-fat diet. These experiments suggest that quercetin can effectively improve the abnormal expression of inflammatory factors caused by high fat.

Protection of the heart

Quercetin has been shown to lower blood pressure, enhance capillary resistance, reduce capillary fragility, lower blood lipids, dilate coronary arteries, and increase coronary blood flow, and also has adjuvant therapeutic effects in patients with coronary heart disease and hypertension.  

Quercetin effectively attenuates H2O2-mediated oxidative damage in cardiomyocytes, which in turn inhibits cardiomyocyte apoptosis. Treatment with quercetin significantly reduced the number of premature ventricular contractions, suggesting a significant cardioprotective effect of quercetin in coronary artery disease.

Improving cardiac function and reducing myocardial hypertrophy: the dietary polyphenol complex quercetin can effectively regulate plasma cholesterol and non-adaptive myocardial remodeling. In addition, inhibition of myocardial hypertrophy can effectively reduce mortality from cardiovascular disease.

Antiplatelet and prevent thrombosis: quercetin can effectively inhibit the formation of thrombus in diabetes, and can be used as an antiplatelet agent in diabetes treatment. It can also inhibit platelet aggregation and agonist-induced GPIIb/IIIa activation caused by collagen, adenosine diphosphate, and arachidonic acid, and quercetin can also inhibit the extracellular secretion of platelet granules.

Vasodilatation and blood pressure lowering: quercetin can lower blood pressure by reducing the elasticity of blood vessels.

Anti-atherosclerosis: quercetin can significantly reduce atherosclerotic plaque areas in the high-fat group, attenuate oxidative stress in various systems, and block the activation of NADPH oxidase, which suggests that regular consumption of quercetin in the diet plays an important role in inhibiting the formation of atherosclerosis. Quercetin can inhibit oxidant-induced endothelial dysfunction and atherosclerosis.

Lowering blood lipids and lipid peroxidation: quercetin has a certain effect of lowering blood lipids, can promote cell proliferation, and reduce triglycerides. And can inhibit the increase of lipid peroxidation, effectively reduce the accumulation of triglycerides in non-alcoholic fatty liver, insulin resistance, and the secretion of some inflammatory factors, and increase the antioxidant capacity of cells, with the increase of quercetin concentration, cholesterol concentration in red blood cells is getting lower.

Prevent myocardial ischemia-reperfusion injury: quercetin pretreatment can significantly improve myocardial function and reduce myocardial injury and infarct area while improving the improvement of oxidative damage and apoptosis of myocardium.

Hypoglycemia and alleviate insulin resistance: Quercetin can effectively improve hyperglycemia and hyperlipidemia and antioxidant status in type 2 diabetes by alleviating blood glucose uptake and improving insulin resistance status through the AMPK pathway rather than the insulin signaling pathway. In addition, quercetin induces an increase in intracellular calcium ion concentration. And AMPK pathway can play a role in reducing insulin resistance through insulin system bypass.

Effects on exercise

Exercise fatigue is associated with oxidative stress during human exercise, and studies before 2017 showed that exercise fatigue can lead to a reduction in the body’s antioxidant capacity and oxidative stress damage. The powerful antioxidant activity of quercetin may also help to reduce fatigue.

Quercetin supplementation may reduce lipid peroxidation damage by decreasing MDA levels during exercise. In addition, quercetin improves the antioxidant capacity of the body by inhibiting the decrease in SOD and GSH-Px during exercise, thereby delaying fatigue.

Antiviral activity

Quercetin significantly reduced the replication rate of hepatitis C virus, while the infectivity of quercetin-treated virus particles was found to be reduced by 65%, indicating that quercetin affected the integrity of the virus, and it was further confirmed by molecular-level experiments that quercetin could exert antiviral effects by blocking the upregulation of diacylglycerol acyltransferase by hepatitis C virus and the typical localization of hepatitis C virus core protein on the surface of lipid droplets.


Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

CEO Email: inquiry@sincerechemical.com

CEO Phone Number:
+86-188-6575 9396

CEO WhatsApp:
+86-188-6575 9396

Request A Free Quote

Keywords of Quercetin

Quercetin, 117-39-5, buy Quercetin, Quercetin supplier, purchase Quercetin, Quercetin cost, Quercetin manufacturer, order Quercetin, high purity Quercetin


United Kingdom Giles
United Kingdom Giles
Read More
Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
Read More
In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
Read More
Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
USA Franklin
USA Franklin
Read More
Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
Canada Kate
Read More
I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
Read More
Sincere Chemical is a reliable and professional company. Not only on exporting but also their professional team service. Their team gave us so many suggestions for our new project. We are really satisfied with their awesome service and best product quality. Sincere-Chem’s vendor code is 51465768 in our cooperated vendor list system.
Read More
I have visited Sincere Chemical company in the year 2018. Their company can be considered as one of the most professional, customer-focused, and product quality-driven companies that I have worked with in recent years.
Brazil Aline
Brazil Aline
Read More
We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
Mexico Gonzalo
Read More
Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...