(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7

(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one, Promotion Season Now in Store and Free Sample for Testing with Factory Price
  • Appearance: White to off Crystal or powder
  • Assay: 99. 0%min
  • Packaging: 25kg/cardboard drums.
  • Sample: Available
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(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
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(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one: The Complete Guide

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Quality Control of Bretazenil(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one

Quality Control & MSDS
Chemical Structure
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
Packing of (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one CAS# 954109-20-7
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Basic Info of (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one

Basic Info

Chemical Name

(S)-3-{(R)-2-[(S)-[4-(benzyloxy)phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)[1,3]dioxolan-2-yl]butanoyl}-4-phenyl-oxazolidin-2-one

Synonyms

(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one;

CAS No.

954109-20-7

Molecular Formula

C42H38F2N2O6

Molecular Weight

704.75800

PSA

86.33000

LogP

8.72420

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What is (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one which has developed particularly rapidly in recent years. Do you know about (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one?

 

The official answer:By selectively inhibiting small intestinal cholesterol transport protein, it effectively reduces cholesterol absorption in the intestine and lowers plasma cholesterol levels as well as hepatic cholesterol stores.

The combination of ezetimibe and low to medium strength statin can inhibit both cholesterol absorption and synthesis, and the two mechanisms are complementary and synergistic, which can reduce LDL-C by more than 50%, providing a new option for intensive clinical lipid-lowering therapy; and the safety and tolerability of the combination are comparable to that of statin monotherapy. According to the 2015 Chinese Expert Recommendations on Cholesterol-lowering Drug Combinations, based on the results of IMPROVE-IT, the SHARP study, and the Cholesterol-lowering Treatment Collaborative Group meta-analysis, ASCVD patients can consider the initial combination of ezetimibe 10 mg and regular dose statin cholesterol-lowering therapy to achieve the LDL-C target in very high-risk patients such as post-PCI patients and patients with coronary heart disease combined with diabetes, and adhere to the therapy for a long time. standard, and long-term adherence to treatment. The combination of ezetimibe and low to moderate-dose statin therapy can also be chosen for patients who cannot achieve the cholesterol target with statins alone or cannot tolerate higher dose statin therapy.

What’s the application of (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one?

  1. Primary hypercholesterolemia

It is used as an adjunct to dietary control, either alone or in combination with HMG-CoA reductase inhibition (statins) for the treatment of primary (heterozygous familial or non-familial) hypercholesterolemia, to reduce total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B (Apo B).

  1. Pure-hereditary familial hypercholesterolemia (HoFH)

It is used in combination with statins as an adjunct to other lipid-lowering therapies (e.g. LDL-C plasma isolation and replacement method) or to lower TC and LDL-C levels in patients with HoFH when other lipid-lowering therapies are ineffective.

  1. Pure subglutathionemia (or phytosterolemia)

This product is used as adjunctive therapy in addition to dietary control to reduce glutathione and phytosterol levels in patients with pure subfamilial glutathioneemia.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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Keywords of (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one

(S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one, 954109-20-7, buy (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one, (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one supplier, purchase (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one, (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one cost, (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one manufacturer, order (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one, high purity (S)-3-{(R)-2-[(S)-(4-(benzyloxyphenyl))-(4-fluorophenylamino)methyl]-4-[2-(4-fluorophenyl)-[1,3]-dioxolan-2-yl]butyryl}-4-phenyloxazolidin-2-one

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United Kingdom Giles
United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
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Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
USA Franklin
USA Franklin
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Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
Unilever
Unilever
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Sincere Chemical is a reliable and professional company. Not only on exporting but also their professional team service. Their team gave us so many suggestions for our new project. We are really satisfied with their awesome service and best product quality. Sincere-Chem’s vendor code is 51465768 in our cooperated vendor list system.
Dupont
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I have visited Sincere Chemical company in the year 2018. Their company can be considered as one of the most professional, customer-focused, and product quality-driven companies that I have worked with in recent years.
Brazil Aline
Brazil Aline
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We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...
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