Vitamin E CAS# 59-02-9
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- Appearance: White or almost white crystal powder
- Assay: 50%min, 400IU, 1000IU, 1400IU
- Packaging: 190kg/Steel Drum.
- Sample: Available
Vitamin E: The Complete Guide
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Quality Control of Vitamin E
Quality Control & MSDS
Chemical Structure
Packing of Bretazenil
Description of Vitamin E
α-Tocopherol is a type of tocopherol or vitamin E. It has E number “E307”.
α-Tocopherol is a form of vitamin E that is preferentially absorbed and accumulated in humans. The measurement of “vitamin E” activity in international units (IU) was based on fertility enhancement by the prevention of spontaneous abortions in pregnant rats relative to alpha-tocopherol.
There are three stereocenters in alpha-tocopherol, so this is a chiral molecule. The eight stereoisomers of alpha-tocopherol differ in the arrangement of groups around these stereocenters. In the image of RRR-alpha-tocopherol, all three stereocenters are in the R form. However, if the middle of the three stereocenters were changed (so the hydrogen was now pointing down and the methyl group pointing up), this would become the structure of RSR-alpha-tocopherol. RSR-alpha-tocopherol and RRR-alpha-tocopherol are diastereomers of each other. These stereoisomers can also be named in an alternative older nomenclature, where the stereocenters are either in the d or l form.
1 IU of tocopherol is defined as ⅔ milligrams of RRR-alpha-tocopherol (formerly named d-alpha-tocopherol or sometimes ddd-alpha-tocopherol). 1 IU is also defined as 1 milligram of an equal mix of the eight stereoisomers, which is a racemic mixture called all-rac-alpha-tocopheryl acetate. This mix of stereoisomers is often called dl-alpha-tocopheryl acetate, even though it is more precisely dl,dl,dl-alpha-tocopheryl acetate). However, 1 IU of this racemic mixture is not now considered equivalent to 1 IU of natural (RRR) α-tocopherol, and the Institute of Medicine and the USDA now convert IU’s of the racemic mixture to milligrams of equivalent RRR using 1 IU racemic mixture = 0.45 “milligrams α-tocopherol”.
Basic Info of Bretazenil
Basic Info
Chemical Name | (+)-α-tocopherol |
Synonyms | (+)-alpha-tocopherol;(+)-α-Tocopherol;D-α-Tocopherol;2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R-[2R*(4R*,8R*)]]-; |
CAS No. | 59-02-9 |
Molecular Formula | C29H50O2 |
Molecular Weight | 430.70600 |
PSA | 29.46000 |
LogP | 8.84020 |
Safety Info
RTECS | DJ2900000 |
Safety Statements | S23-S24/25 |
HS Code | 2936280000 |
WGK Germany | 1 |
Risk Statements | R36/37/38 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | light yellow liquid |
Density | 0.93 |
Boiling Point | 200-220ºC (0.07501 mmHg) |
Melting Point | 2.5-3.5ºC |
Flash Point | 253ºC |
Refractive Index | n20/D 1.505(lit.) |
Stability | Stable. Combustible. May be sensitive to light and air. Incompatible with strong oxidizing agents. |
Storage Condition | 2-8ºC |
Vapor Pressure | 4.59E-10mmHg at 25°C |
Numbering system
MDL number | MFCD00072045 |
What is Vitamin E?
Part I: Introduction
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Vitamin E which has developed particularly rapidly in recent years. Do you know about Vitamin E?
The official answer: Tocopherol is a hydrolysis product of vitamin E. All natural tocopherols are d-tocopherols (dextro type), which have 8 isomers such as α, β, ϒ and δ, among which α-tocopherol is the most active. The d-mixed-tocopherol concentrate used as an antioxidant is a mixture of the various isomers of natural tocopherols.
What’s the application of Vitamin E?
Part 2: In-depth development
Increases the antioxidant effect of cells and maintains and promotes reproductive functions. It has certain anti-aging effects and also improves lipid metabolism, prevents atherosclerosis, and lowers blood lipids.
Commonly used for the prevention of habitual and pre-eclampsia miscarriages, and the treatment of the menopausal syndrome. It is used for the adjuvant treatment of hepatitis, liver cirrhosis, and myotonic dystrophy.
Dosage: 5mg, 50mg per tablet, 2-3 times daily, 10-100mg once.
Side effects and precautions: Adverse reactions are rarely seen with normal doses. Nausea, vomiting, gastrointestinal disorders, headache, dizziness, blurred vision, menstrual disorders, prolonged clotting time in individual patients may be seen with a long-term heavy application for more than six months.
Conclusion
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