2,3-Pyrazinedicarboxylic acid CAS 89-01-0

Products Name

2,3-Pyrazinedicarboxylic acid

Products Description
CAS No.: 89-01-0

Chemical Name: 2,3-Pyrazinedicarboxylic acid

Molecular Formula: C6H4N2O4

Molecular Weight: 168.11

Appearance: White crystal

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2,3-Pyrazinedicarboxylic acid Typical Properties


off-white to yellowish  crystalline powder
Off-white crystalline powder

Moisture content


Assay ( By Titrimetry)

2,3-Pyrazinedicarboxylic acid Molecular formula

2,3-Pyrazinedicarboxylic acid production method
It is derived from benzopyrazine as raw material by oxidation of potassium permanganate. First put water and benzopyrazine into the reaction pot, add potassium permanganate uniformly under stirring, keep the temperature at 68-70℃ for 2h, and measure the end point.
Let it stand overnight, absorb the supernatant liquid, add water to the lower layer and stir, heat to 80°C and filter. Concentrate the supernatant and filtrate with a thin film evaporator, then take it out and neutralize it with hydrochloric acid to pH=2, and precipitate monopotassium pyrazine dicarboxylate Salt, cool, and filter at 25°C.
The filter cake was added to hydrochloric acid, stirred and heated to complete dissolution, cooled and crystallized below 15°C, filtered by shaking, washed with a little ethanol, and dried to obtain crystals. Based on benzopyrazine, the yield is 70%
2,3-Pyrazinedicarboxylic acid Usage
Used as an intermediate for the synthesis of pyrazinamide This product is an intermediate for the anti-tuberculosis drug pyrazinamide.
This product is an intermediate of the anti-tuberculosis drug pyrazinamide.
2,3-Pyrazinedicarboxylic acid Chemical nature
Those with two molecules of crystal water are columnar crystals. Easily soluble in water, soluble in methanol, acetone, ethyl acetate, slightly soluble in ethanol, ether, chloroform, benzene and petroleum ether.
2,3-Pyrazinedicarboxylic acid Packaging and Shipping
Packing: 25kg/drum
2,3-Pyrazinedicarboxylic acid Storage
Stored in cool dry ventilated place away from fire, heat, light, acids and food materials


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