4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE CAS 15646-46-5

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE, Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name: 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
CAS No.: 15646-46-5
Molecular Fomula: C12H11NO3
Molecular weight: 217.22
Appearance: neat
Sample: Available

4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE CAS 15646-46-5

Description of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

There are many methods to extract Oxazolone, mainly alcohol precipitation method, heavy metal separation method, dilute acid extraction method, etc. At present, the dilute acid extraction method is mostly used in industry. In other words, the raw material is soaked with dilute inorganic acid and then neutralised and precipitated with alkali solution to obtain a paste-like Oxazolone product.

Basic Info of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

Chemical Name

4-(ethoxymethylene)-2-phenyloxazol-5-one

Synonyms

4-Ethoxymethylene-2-phenyloxazolin-5-one;4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE;4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5-one;

CAS No.

15646-46-5

Molecular Formula

C12H11NO3

Molecular Weight

217.22100

PSA

47.89000

LogP

1.30350

Safety Info

RTECS

RQ5786250

Safety Statements

S36

HS Code

2934999090

WGK Germany

3

Risk Statements

R43

Hazard Codes

Xn

Properties

Appearance & Physical State

WHITE TO ORANGE TO TAN POWDER AND/OR CHUNKS

Density

1.18 g/cm3

Boiling Point

308.8ºC at 760 mmHg

Melting Point

94-96ºC

Flash Point

136.8ºC

Refractive Index

1.561

Storage Condition

2-8ºC

Vapor Pressure

0.000666mmHg at 25°C

Numbering system

PubChem number

24894371

EINECS number

239-713-9

BRN number

163055

RTECS number

RQ5786250

MDL number

MFCD00003204

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What is 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE?

     With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Oxazolone which has developed particularly rapidly in recent years. Do you know about Oxazolone?

The official answer: Oxazolone is a commonly used anti-tuberculosis drug, also known as sodium p-aminosalicylate, Oxazolone, PAS-Na, white or off-white crystalline powder, odourless, sweet and salty, easily soluble in water, slightly soluble in ethanol, insoluble in acetone, almost insoluble in ether, chloroform, benzene. 2% aqueous solution pH 6.5-8. Aqueous solution is easily decarbonated to m-aminophenol. Phenol, so it should be freshly prepared when used. This product is similar in structure to p-aminobenzoic acid (PABA) and is a similar product to p-aminobenzoic acid (PABA), which inhibits the growth and reproduction of Mycobacterium tuberculosis through competitive inhibition of folic acid synthesis.

What’s the application of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE?

For pulmonary and extrapulmonary tuberculosis due to Mycobacterium tuberculosis. 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE is effective only against Mycobacterium tuberculosis and not against non-tuberculous mycobacteria. When used alone, resistance can develop rapidly and must be combined with other anti-tuberculosis drugs. Streptomycin and isoniazid, when used in combination, can delay the development of resistance to the former two drugs in Mycobacterium tuberculosis. They are mainly used as second-line anti-tuberculosis drugs.

Conclusion

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Keywords of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

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