4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE CAS 15646-46-5
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE, Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name: 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
CAS No.: 15646-46-5
Molecular Fomula: C12H11NO3
Molecular weight: 217.22
Appearance: neat
Sample: Available
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE: The Complete Guide
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Description of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
There are many methods to extract Oxazolone, mainly alcohol precipitation method, heavy metal separation method, dilute acid extraction method, etc. At present, the dilute acid extraction method is mostly used in industry. In other words, the raw material is soaked with dilute inorganic acid and then neutralised and precipitated with alkali solution to obtain a paste-like Oxazolone product.
Basic Info of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE
Chemical Name | 4-(ethoxymethylene)-2-phenyloxazol-5-one |
Synonyms | 4-Ethoxymethylene-2-phenyloxazolin-5-one;4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE;4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5-one; |
CAS No. | 15646-46-5 |
Molecular Formula | C12H11NO3 |
Molecular Weight | 217.22100 |
PSA | 47.89000 |
LogP | 1.30350 |
Safety Info
RTECS | RQ5786250 |
Safety Statements | S36 |
HS Code | 2934999090 |
WGK Germany | 3 |
Risk Statements | R43 |
Hazard Codes | Xn |
Properties
Appearance & Physical State | WHITE TO ORANGE TO TAN POWDER AND/OR CHUNKS |
Density | 1.18 g/cm3 |
Boiling Point | 308.8ºC at 760 mmHg |
Melting Point | 94-96ºC |
Flash Point | 136.8ºC |
Refractive Index | 1.561 |
Storage Condition | 2-8ºC |
Vapor Pressure | 0.000666mmHg at 25°C |
Numbering system
PubChem number | 24894371 |
EINECS number | 239-713-9 |
BRN number | 163055 |
RTECS number | RQ5786250 |
MDL number | MFCD00003204 |
What is 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Oxazolone which has developed particularly rapidly in recent years. Do you know about Oxazolone?
The official answer: Oxazolone is a commonly used anti-tuberculosis drug, also known as sodium p-aminosalicylate, Oxazolone, PAS-Na, white or off-white crystalline powder, odourless, sweet and salty, easily soluble in water, slightly soluble in ethanol, insoluble in acetone, almost insoluble in ether, chloroform, benzene. 2% aqueous solution pH 6.5-8. Aqueous solution is easily decarbonated to m-aminophenol. Phenol, so it should be freshly prepared when used. This product is similar in structure to p-aminobenzoic acid (PABA) and is a similar product to p-aminobenzoic acid (PABA), which inhibits the growth and reproduction of Mycobacterium tuberculosis through competitive inhibition of folic acid synthesis.
What’s the application of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE?
For pulmonary and extrapulmonary tuberculosis due to Mycobacterium tuberculosis. 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE is effective only against Mycobacterium tuberculosis and not against non-tuberculous mycobacteria. When used alone, resistance can develop rapidly and must be combined with other anti-tuberculosis drugs. Streptomycin and isoniazid, when used in combination, can delay the development of resistance to the former two drugs in Mycobacterium tuberculosis. They are mainly used as second-line anti-tuberculosis drugs.
Conclusion
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