Apixaban CAS 503612-47-3
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Chemical Name: Apixaban
CAS No.: 503612-47-3
Molecular Fomula: C25H25N5O4
Molecular weight:459.5
Appearance: neat
Sample: Available
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Description of Apixaban
Apixaban, sold under the tradename Eliquis, is an anticoagulant for the treatment of venous thromboembolic events. It is taken by mouth. It is a direct factor Xa inhibitor.
Apixaban was approved in Europe in 2012. It was approved in the U.S. in 2014 for treatment and secondary prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is being developed in a joint venture by Pfizer and Bristol-Myers Squibb.
Basic Info of Apixaban
Chemical Name | apixaban |
Synonyms | 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide;Eliquis;xaban;UNII-3Z9Y7UWC1J; |
CAS No. | 503612-47-3 |
Molecular Formula | C25H25N5O4 |
Molecular Weight | 459.49700 |
PSA | 110.76000 |
LogP | 3.52990 |
Properties
Density | 1.42g/cm3 |
Boiling Point | 770.468ºC at 760 mmHg |
Flash Point | 419.764ºC |
Refractive Index | 1.705 |
Numbering system
MDL number | MFCD11977295 |
What is Apixaban ?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is xaban which has developed particularly rapidly in recent years. Do you know about xaban?
- The official answer:xaban is a new oral factor Xa inhibitor co-developed by Bristol-Myers Squibb and Pfizer, under the trade name Eladol, is a new oral anticoagulant. By inhibiting an important coagulation factor Xa, xaban prevents thrombin production and thrombosis. xaban is the third new oral anticoagulant to be marketed after dabigatran and rivaroxaban. It is approved in Europe for the prevention of venous thromboembolic events in patients undergoing elective hip or knee replacement surgery.
What’s the application of Apixaban ?
xaban is an oral selective activated factor X inhibitor that prevents thrombosis but has a lower adverse effect on bleeding than the older drug warfarin and is used for thrombosis prophylaxis in patients who have undergone hip or knee replacement surgery.
(1) Nursing mothers: Discontinue the drug or discontinue breastfeeding.
(2) Pregnancy: Not recommended.
(3) Severe hepatic impairment: not recommended.
Conclusion
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