AtracuriuM Besylate CAS 64228-79-1
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Chemical Name: AtracuriuM Besylate
CAS No.: 64228-79-1
Molecular Fomula: C53H72N2O12
Molecular weight:929.14
Appearance: White to yellowish white powder
Sample: Available
AtracuriuM Besylate: The Complete Guide
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Description of AtracuriuM Besylate
The benzene sulfonate is a white to yellowish-white powder with slight hygroscopicity. It is soluble in water and very soluble in ethanol, acetonitrile and dichloromethane. It contains three isomers: cis-cis, cis-trans and trans-trans.
Basic Info of AtracuriuM Besylate
Chemical Name | atracurium |
Synonyms | 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate;Atracurium;UNII-2GQ1IRY63P;Atracurium Dibesylate; |
CAS No. | 64228-79-1 |
Molecular Formula | C53H72N2O12++ |
Molecular Weight | 929.14500 |
PSA | 126.44000 |
LogP | 7.98310 |
Properties
Melting Point | 185-194ºC |
Numbering system
UNII | 2GQ1IRY63P |
What is AtracuriuM Besylate?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Atracurium which has developed particularly rapidly in recent years. Do you know about Atracurium?
- The official answer:Atracurium is a moderately chronotropic non-depolarising muscle relaxant and is commonly used as its benzenesulphonate salt. It is mainly eliminated by non-enzymatic degradation, but can also be hydrolysed by pseudocholinesterase to inactive metabolites, which are then excreted via the kidneys and bile. The effect is weaker than that of the cartridge, but the onset of action is rapid (1 minute), the duration is short (15 minutes), there is no accumulation of repeated doses, the effect on ganglion blockade is mild and there is no effect on heart rate.
What’s the application of AtracuriuM Besylate?
Primarily used as a skeletal relaxant during anaesthesia in various surgical procedures to facilitate controlled breathing, and particularly indicated for the muscle relaxation required during tracheal intubation. Maintenance of muscle relaxation for caesarean section.
It is used clinically for various surgical procedures where inotropic relaxation is required to facilitate controlled breathing administered by sedation at a starting dose of 0.3 to 0.6 mg/kg, which can then be maintained by sedation at 5 to 10 μg/kg per minute.
Conclusion
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