Clomifene CAS# 911-45-5

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Chemical Name: Clomifene

CAS No.:  911-45-5

Molecular Fomula: C26H28ClNO

Molecular weight:405.96

Appearance: White powder

Clomifene CAS# 911-45-5

Description of Clomifene

Clomifene (INN) or clomiphene (USAN) (trademarked as Androxal, Clomid and Omifin, citrate salt Serophene) is a selective estrogen receptor modulator (SERM) of the triphenylethylene group that has become the most widely prescribed drug for ovulation induction to reverse anovulation or oligoovulation.
It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Basic Info of Ambroxan

Chemical Name

clomiphene

Synonyms

Clomiphene,E/Z-mixture;Clomiphene B;E/Z-CloMiphene-d4;Clomifene;Clomiphene;

CAS No.

911-45-5

Molecular Formula

C26H28ClNO

Molecular Weight

405.96000

PSA

12.47000

LogP

6.56260

Properties

Density

1.104g/cm3

Boiling Point

509ºC at 760mmHg

Flash Point

261.6ºC

Refractive Index

1.588

Numbering system

MDL number

MFCD00599444

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What is Clomifene?

  • With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Clomifene which has developed particularly rapidly in recent years. Do you know about Clomifene?
  • Clomiphene, is a chemical. The chemical name is N,N-diethyl-2-[4-(1,2-diphenyl-2-chlorovinyl)phenoxy]ethylamine, molecular formula is C26H28ClNO, molecular weight is 405.96000, density is 1.104g/cm3, boiling point is 509ºC at 760mmHg. clomiphene has strong anti-estrogenic effect and weak estrogenic activity clinically mainly It is mainly used for amenorrhea and menstrual disorders caused by contraceptives.

What’s the application of Clomifene?

  • Clomiphene is an antiestrogen thought to increase sperm parameters in males attempting to conceive. The objective of this review was to evaluate the efficacy and safety of Clomiphene citrate in the treatment of male patients with infertility. It is an oral agent used to treat infertility in women desiring pregnancy. Clomiphene has been linked to a low rate of transient serum aminotransferase elevations during therapy and to rare instances of clinically apparent liver injury, which can be severe and even fatal.A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
  • Clomifene is used for infertility in order to increase reproductive properties of oligoovulatory women who have three or four ovulatory cycles per year, leading to normal monthly ovulation.

Conclusion

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