Diazolidinyl urea cas 78491-02-8


Description Diazolidinyl urea Diazolidinyl Urea Quick Details Chemical Name: Diazolidinyl Urea CAS No.: 78491-02-8 Appearance: White Powder Molecular Formula: C8H14N4O7 Molecular weight: 278.22 Chemical Structure: Assay: 19.0~21.0% Diazolidinyl Urea Typical Properties Item Standard Appearance white powder with special smell Purity(Nitrogen) 19.0~21.0% Ashes ≤ 3.0% Loss On Dry ≤3.0% Ph 6.0-8.0 Diazolidinyl Urea Mold resistance Broad spectrum antimicrobial activity for restrain of gram negative and positive bacteria, saccharomycetes and mould. Diazolidinyl Urea Usage 1. used in cream, emulsion, shampoo and wet tissure. 2. dosage: 0.1~0.4% 3. PH range for application: 3~9 4. used together with surface active agent, protein and most cosmetics. Diazolidinyl Urea Packaging and Shipping Packing: 25KG/fiber can or on demand 25kg/drum Delivery: delivery within 3-5working days Diazolidinyl Urea Storage preserved in cool and dry place sealed, shelf life is 24 months.
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Chemical Name: Diazolidinyl Urea
CAS No.: 78491-02-8
Molecular Fomula:C8H14N4O7
Molecular weight: 278.22
Appearance: White powder


Description of GERMALL A

Diazolidinyl urea is an antimicrobial preservative used in cosmetics. It is chemically related to imidazolidinyl urea which is used in the same way. Diazolidinyl urea acts as a formaldehyde releaser.
It is used in many cosmetics, skin care products, shampoos and conditioners, as well as a wide range of products including bubble baths, baby wipes and household detergents. Diazolidinyl urea is found in the commercially available preservative Germaben.
Commercial diazolidinyl urea is a mixture of different formaldehyde addition products including polymers.

Basic Info of GERMALL A

Basic Info

Chemical Name

Diazolidinyl urea





Molecular Formula


Molecular Weight






Safety Info



Safety Statements


HS Code


WGK Germany


Risk Statements


Hazard Codes



Appearance & Physical State

white powder, free-flowing


1.83 g/cm3

Refractive Index



Stable. Incompatible with strong oxidizing agents.

Storage Condition


Numbering system
MDL numberMFCD03547942
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What is GERMALL A?

  • With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Diazolidinyl Urea which has developed particularly rapidly in recent years. Do you know about Diazolidinyl Urea?
  • The official answer: Diazolidinyl urea is a chemical substance with the molecular formula C8H14N4O7.

What’s the application of GERMALL A?

  • Diazolidinyl urea has broad-spectrum antibacterial activity and can inhibit Gram-negative and positive bacteria, and has some inhibitory effect on yeast and mold. Diazolidinyl urea can be used in creams, lotions, shampoos, hair conditioners, liquid cosmetics and eye cosmetics, and other attaching and wash-off products, which are approved by the Chemical book of the US and EU.
  • The general addition amount is 0.1~0.3%, and it is better to add below 50℃, and it can be used with nipagin ester and IPBC to enhance its anticorrosive effect. Used in cosmetics, food processing, and feed industry, etc. for corrosion protection.


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  • Diazinon is not a beneficial ingredient for the skin. It does not work like vitamin C or vitamin A. Diazinonylurea is only used to improve the safety and longevity of products and to protect them from yeast, mold, and bacteria.
  •   Preservatives are an important part of the formulation process because they ensure that your product is protected from contamination. Contamination may occur unintentionally through use or exposure to air. Ensuring that bacteria, yeast, and mold are prevented means that products can be used safely for longer periods of time. Without preservatives, most products will expire within a few weeks.
Yes, Diazolidinyl urea is considered safe for acne. It is not suspected to cause irritation or increase the severity of outbreaks or eruptions.
  • Diazolidinyl Urea can be a formaldehyde-releasing preservative. While this may sound scary, the reality is that the amount of formaldehyde released is well below the recommended exposure limits. According to one study, exposure to formaldehyde using a formaldehyde-releasing preservative is similar to eating a pear.
  •  There is also evidence that the proteins and other ingredients contained in the product actually cause the formaldehyde to evaporate or become inactive before it can cause any harm to the body.
  • Yes, diazinon urea is considered a vegan ingredient because it is usually produced for real. Keep in mind that the other ingredients in the formulation will determine if the product contains vegan ingredients.
  •  Another thing to consider when looking for vegan products is whether they are cruelty-free. This information is usually easily available on the packaging or on the brand’s website.
  • The safety of Diazolidinyl urea has been evaluated by the Cosmetic Ingredient Review Panel, which is responsible for reviewing the safety of skincare and cosmetic ingredients. The panel reviewed the available data on Diazolidinyl urea and found the ingredient to be safe for its current use and concentration.
  •  Studies conducted by the Cosmetic Ingredient Review Panel on Diazolidinyl urea determined it to be less irritating to the eyes. However, it was not found to be sensitive to the skin or to produce phototoxic effects. Its use is limited to a maximum concentration of 0.5%. This concentration limit is primarily due to the slight irritation that may occur on the skin at concentrations above this maximum.
  •   In 2006, the Cosmetic Ingredient Review Panel reviewed any new data and reaffirmed the above conclusions regarding the safety of this ingredient.

Diazolidinyl urea is an antimicrobial preservative that acts by forming formaldehyde in cosmetic products. The formaldehyde thus formed serves to protect cosmetic preparations from microbial attack. Many cosmetic formulations use Diazolidinyl urea as a preservative. However, even at very low concentrations, some people can become allergic to formaldehyde exposure due to the use of formaldehyde-releasing preservatives in cosmetics. Sensitive individuals should be cautious in choosing cosmetic products containing diazinon urea formulations.


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