Eszopiclone CAS#138729-47-2
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Chemical Name: Eszopiclone
CAS No.:138729-47-2
Molecular Formula C17H17ClN6O3
Average mass 388.808
Appearance: White or slightly yellowish powder
Sample: Available
Eszopiclone : The Complete Guide
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Description of Eszopiclone
Eszopiclone, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic which is slightly effective for insomnia. Eszopiclone is the active dextrorotatory stereoisomer of zopiclone, and belongs to the class of drugs known as cyclopyrrolones.
Eszopiclone (Lunesta) along with other “Z-drugs” including zolpidem (Ambien), zaleplon (Sonata) are the most commonly prescribed sedative hypnotics in the United States. Eszopiclone is not marketed in the European Union following a 2009 decision by the EMA denying it new active substance status, in which it ruled that eszopiclone was too similar to zopiclone to be considered a new patentable product.
Eszopiclone is now available in a generic form in the United States as of May 2014. On May 15, 2014, the USFDA asked that the starting dose of Eszopiclone (Lunesta) be lowered from 2 milligrams to 1 milligram after it was observed in a study that even 8 hours after taking the drug at night, some patients were not able to cope with their next-day activities like driving and other activities that require full alertness.
Basic Info of Eszopiclone
Chemical Name | eszopiclone |
|---|---|
Synonyms | Estorra;Esopiclone;UNII-UZX80K71OE;[(7S)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate;Eszopiclone;Expand |
CAS No. | 138729-47-2 |
Molecular Formula | C17H17ClN6O3 |
Molecular Weight | 388.80800 |
PSA | 91.76000 |
LogP | 1.50880 |
Safety Info
Safety Statements | S26-S36 |
|---|---|
HS Code | 2933599090 |
Risk Statements | R20/21/22; R36/37/38; R62 |
Hazard Codes | Xn |
Properties
Appearance & Physical State | White or slightly yellowish powder |
|---|---|
Density | 1.54 g/cm3 |
Boiling Point | 580.7ºC at 760 mmHg |
Melting Point | 202-204ºC |
Flash Point | 305ºC |
Refractive Index | 1.688 |
Vapor Pressure | 1.78E-13mmHg at 25°C |
Numbering system
| MDL number | MFCD03700720 |
|---|
What is Eszopiclone?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ambroxan which has developed particularly rapidly in recent years. Do you know about Ambroxan?
The official answer: Dexzopiclone, an organic compound with the chemical formula C17H17ClN6O3, is a white or slightly pale yellow powder.
What’s the application of Eszopiclone?
It is used for the treatment of people with insomnia, difficulty falling asleep or difficulty maintaining sleep.
Conclusion
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