Isonicotinic acid CAS 55-22-1
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Chemical Name: Isonicotinic acid
Appearance:yellow to tan powder
Isonicotinic acid: The Complete Guide
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Description of Isonicotinic acid
INA or 4-pyridinecarboxylic acid is an organic compound with the formula C5H4N(CO2H). It is a derivative of pyridine with a carboxylic acid substituent at the 4-position. It is an isomer of picolinic acid and nicotinic acid which has the carboxyl group at the 2nd and 3rd position respectively compared to the 4-position for nicotinic acid.
Basic Info of Isonicotinic acid
INA;4-Pyridinecarboxylic acid;pyridine-4-carboxylic acid;
Appearance & Physical State
White to off-white crystalline solid
260ºC (15 mmHg)
5.2 g/L (20 ºC)
Stable under normal temperatures and pressures.
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
What is Isonicotinic acid?
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The official answer:4-Pyridinecarboxylic acid, also known as isonicotinic acid; pyridine-4-carboxylic acid; isonicotinic acid, a chemical substance
What’s the application of Isonicotinic acid?
Isonicotinic acid is a widely used intermediate, mainly as a raw material for first-line anti-tuberculosis drugs such as isoniazid (Remifentan), terfenadine and isonicotinate, but also as an anti-corrosion agent, electroplating additive, photographic resin stabilizer, PVC heat stabilizer and non-ferrous metal flotation agent, etc. Isonicotinic acid is produced by condensing Chemicalbook with hydrazine hydrate and melting and dehydrating. Isonicotinic acid has good antibacterial effects on Mycobacterium tuberculosis, with good efficacy, small dosage and relatively low toxicity, and is used in the progressive, dissolution and dissemination phases of all types of pulmonary tuberculosis, as well as in tuberculous meningitis and other extrapulmonary tuberculosis, etc. Preparations include tablets and injections.
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