Latanoprost CAS# 130209-82-4
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Latanoprost : The Complete Guide
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Description of Latanoprost
Latanoprost was invented by Johan W. Stjernschantz and Bahram Resul, employees of the Pharmacia Corporation of Uppsala, Sweden. It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system. It is also known by the brand name of Xalatan manufactured by Pfizer. Annual sales are approximately $1.6 billion. The patent for latanoprost expired in March 2011, and at least one generic version is now widely available in the U.S.
Basic Info of Latanoprost
Appearance & Physical State
pale yellow oil
583.8ºC at 760 mmHg
What is Latanoprost?
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The official answer: Latanoprost is a novel phenyl-substituted propyl ester prostaglandin F2a, a selective F2a receptor agonist. It is an inactive but penetrating substance that is hydrolyzed in the cornea and plasma to an active free acid. It can increase the outflow of atrial water through the corneal vegetative layer of the eye, with a small dose, but promotes a large amount of atrial water filling out, and the drug can penetrate into the upper layer of the supraocular ciliary choroid, with good IOP lowering effect.
What’s the application of Latanoprost?
Latanoprost is a prostaglandin. Prostaglandins are commonly characterized by having substituents on the cyclopentane ring. Uses For the treatment of glaucoma.
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