Mecobalamin CAS# 13422-55-4

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Chemical Name: Mecobalamin

CAS No.: 13422-55-4

Molecular Formula C63H91CoN13O14P

Average mass 1344.3823

Appearance: Partially soluble in cold water, hot water.

.Sample: Available

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Mecobalamin CAS# 13422-55-4

Mecobalamin： The Complete Guide

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Description of Mecobalamin

Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis.
Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia.
Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
Methylcobalamin is not sufficient as a singular source of vitamin B12. Hydroxocobalamin and cyanocobalamin can both be split by the body into methylcobalamin and adenosylcobalamin. Methylcobalamin on the other hand is not converted into adenosylcobalamin. Deficiency of adenosylcobalamin disturbs carbohydrate, fat and amino-acid metabolism, and hence interferes with the formation of myelin. Thereby it is important to treat vitamin B12 deficiency with hydroxocobalamin or cyanocobalamin or a combination of adenosylcobalamin and methylcobalamin.
 

Basic Info of Mecobalamin

Chemical Name

methylcobalamin

Synonyms

methycobal;methyl-b12;Methylcobaz;mbl-a;Algobaz;Expand

CAS No.

13422-55-4

Molecular Formula

C63H91CoN13O14P

Molecular Weight

1344.38000

PSA

463.87000

LogP

7.19930

Safety Info

Safety Statements

S24/25; S36; S26

HS Code

2936260000

Risk Statements

R36/37/38

Hazard Codes

Xi

Numbering system
RTECS numberGG3745000
MDL numberMFCD00082483
EINECS number236-535-3
Properties

Appearance & Physical State

dark red crystalline powder

Storage Condition

-20ºC

What is Mecobalamin?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ambroxan which has developed particularly rapidly in recent years. Do you know about Ambroxan?

The official answer: Methylcobalamin (Mecobalamin) is an endogenous vitamin B12, which is present in blood and myelin. Compared with vitamin B12, it has a good effect on neuronal conduction and can promote nucleic acid-protein-fat metabolism through methyl conversion reaction, and it acts as a coenzyme of methionine synthase, converts homocysteine to methionine, participates in the process of deoxyribonucleoside synthesis of thymine, and It promotes nucleic acid and protein synthesis, promotes intra-axonal transport and axonal regeneration and myelin formation, prevents axonal degeneration, and repairs damaged neural tissue. The peak blood concentration is reached 3 hours after oral administration, and its absorption is dose-dependent. It can be detected sequentially in blood, kidney, adrenal, pancreas, liver, and stomach tissues at higher concentrations, and in muscle, testis, and brain nerves at lower concentrations. The urinary excretion of total B12 8 hours after administration is 40% to 80% of the excretion 24 hours after dosing.

What’s the application of Mecobalamin?

Used for the treatment of neurological disorders, relief of pain and numbness, quick relief of neuralgia, improvement of pain caused by cervical spondylosis, treatment of sudden deafness, etc.
UsesMethylcobalaminChemicalbook is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction for the synthesis of methionine from homocysteine.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates include more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive systems, Santi-tumor, Nervous systems, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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United Kingdom Giles
United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
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Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
USA Franklin
USA Franklin
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Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
Unilever
Unilever
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Sincere Chemical is a reliable and professional company. Not only on exporting but also their professional team service. Their team gave us so many suggestions for our new project. We are really satisfied with their awesome service and best product quality. Sincere-Chem’s vendor code is 51465768 in our cooperated vendor list system.
Dupont
Dupont
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I have visited Sincere Chemical company in the year 2018. Their company can be considered as one of the most professional, customer-focused, and product quality-driven companies that I have worked with in recent years.
Brazil Aline
Brazil Aline
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We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...
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