Mecobalamin CAS# 13422-55-4
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Chemical Name: Mecobalamin
CAS No.: 13422-55-4
Molecular Formula C63H91CoN13O14P
Average mass 1344.3823
Appearance: Partially soluble in cold water, hot water.
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Description of Mecobalamin
Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia.
Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.
Methylcobalamin is not sufficient as a singular source of vitamin B12. Hydroxocobalamin and cyanocobalamin can both be split by the body into methylcobalamin and adenosylcobalamin. Methylcobalamin on the other hand is not converted into adenosylcobalamin. Deficiency of adenosylcobalamin disturbs carbohydrate, fat and amino-acid metabolism, and hence interferes with the formation of myelin. Thereby it is important to treat vitamin B12 deficiency with hydroxocobalamin or cyanocobalamin or a combination of adenosylcobalamin and methylcobalamin.
Basic Info of Mecobalamin
S24/25; S36; S26
Appearance & Physical State
dark red crystalline powder
What is Mecobalamin?
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The official answer: Methylcobalamin (Mecobalamin) is an endogenous vitamin B12, which is present in blood and myelin. Compared with vitamin B12, it has a good effect on neuronal conduction and can promote nucleic acid-protein-fat metabolism through methyl conversion reaction, and it acts as a coenzyme of methionine synthase, converts homocysteine to methionine, participates in the process of deoxyribonucleoside synthesis of thymine, and It promotes nucleic acid and protein synthesis, promotes intra-axonal transport and axonal regeneration and myelin formation, prevents axonal degeneration, and repairs damaged neural tissue. The peak blood concentration is reached 3 hours after oral administration, and its absorption is dose-dependent. It can be detected sequentially in blood, kidney, adrenal, pancreas, liver, and stomach tissues at higher concentrations, and in muscle, testis, and brain nerves at lower concentrations. The urinary excretion of total B12 8 hours after administration is 40% to 80% of the excretion 24 hours after dosing.
What’s the application of Mecobalamin?
Used for the treatment of neurological disorders, relief of pain and numbness, quick relief of neuralgia, improvement of pain caused by cervical spondylosis, treatment of sudden deafness, etc.
UsesMethylcobalaminChemicalbook is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction for the synthesis of methionine from homocysteine.
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