N-Bromosuccinimide CAS 128-08-5

N-Bromosuccinimide, Promotion Season Now in Store and Free Sample for Testing with Factory Price

ChemicalName:VitaminECAS#128-08-5
CASNo.:128-08-5
MolecularFomula:C4H4BrNO2
Moleculareight:177.98
Appearance: White to milky white fine-grained crystals

N-Bromosuccinimide CAS 128-08-5

Description of N-Bromosuccinimide

N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution and electrophilic addition reactions in organic chemistry. NBS can be a convenient source of Br•, the bromine radical.

Basic Info of N-Bromosuccinimide

Chemical Name

N-bromosuccinimide

Synonyms

N-Bromosuccinimide;1-bromopyrrolidine-2,5-dione;N-bromobutanimide;2,5-Pyrrolidinedione, 1-bromo-;

CAS No.

128-08-5

Molecular Formula

C4H4BrNO2

Molecular Weight

177.98400

PSA

37.38000

LogP

0.38320

Safety Info

Hazard Class

8

Safety Statements

S26-S37/39

HS Code

2925190090

Packing Group

III

WGK Germany

3

RIDADR

UN 3261 8/PG 2

Risk Statements

R22; R36/37/38

Properties

Appearance & Physical State

white to off-white powder

Density

2.098

Boiling Point

221.4ºC at 760 mmHg

Melting Point

175-178ºC

Flash Point

87.7ºC

Refractive Index

1.606

Stability

Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.

Storage Condition

0-6ºC

Vapor Pressure

0.107mmHg at 25°C

Appearance & Physical State

white to off-white powder

Density

2.098

Boiling Point

221.4ºC at 760 mmHg

Numbering system

MDL number

MFCD00005510

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What is N-Bromosuccinimide?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product isN-Bromosuccinimide which has developed particularly rapidly in recent years. Do you know aboutN-Bromosuccinimide?

 

The official answer: N-Bromosuccinimide is a five-membered cyclic dicarboximide compound with a bromine substituent on the nitrogen atom [1], also known as N-bromosuccinimide, or NBS for short, with the chemical formula C4H4BrNO2.

What’s the application of N-Bromosuccinimide?

Identification reagents

Used as an identification reagent for primary, secondary and tertiary alcohols.

Raw material for organic synthesis

Widely used in anionic and radical bromination reactions of olefins, alkynes and other compounds. It is used for the regulation of low-energy bromination reactions, for the production of rubber auxiliaries and for the commercial production of pharmaceuticals such as cortisone and vitamin D3, and for the synthesis of thiamethoxam in the pesticide industry.

Preservatives

Used as a preservative for fruit and as a preservative and anti-mould agent.

Important brominating agents

Used in allylic bromination (Wohl-Ziegler reaction) as a selective brominating agent for chain olefins and alkyl aromatics. In the pharmaceutical industry, it is used as a brominating agent in the synthesis of antimicrobial agents such as benzyl cephalosporins (Cefaloram).

Important oxidising agents

Oxidation of ethanol to aldehydes and ketones and oxidation of aldehydes to brominated acids in organic synthesis. Oxidation of silyl ethers to aldehydes in the presence of AIBN. Used in the oxidation of tryptophan, but tyrosine, histidine and methionine residues may be oxidised to a lesser extent.

Tryptophan reformer

Also used for the modification of ribosomal sulfhydryl groups.

General purpose brominating reagents

Used for the oxidation of tryptophan, although tyrosine, histidine and methionine oxidation residues may be present to a lesser extent; used for group modification of ribosomal sulfhydryl groups.

Ascorbic acid determination

Used to determine ascorbic acid in pharmaceutical preparations, biological fluids and vegetables and fruits.

Conclusion

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