Povidone Iodine CAS 25655-41-8

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Chemical Name: Povidone Iodine
CAS No.: 25655-41-8
Molecular Fomula: C6H9I2NO
Molecular weight: 364.95
Appearance: Yellow-brown Powder
Sample: Available

Povidone Iodine: The Complete Guide

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Description of Povidone Iodine

Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than tincture of iodine.
Human clinical trials showed the product to be superior to other iodine formulations.
Betadine was immediately marketed, and has since become the universally preferred iodine antiseptic.
It is on the WHO Model List of Essential Medicines, the most important products needed in a basic health system.

Basic Info of Povidone Iodine

Chemical Name	Povidone iodine
Synonyms	Isobetadyne;I-PVP;Disphex;1-ethenylpyrrolidin-2-one,molecular iodine;Polyvinylpyrrolidone-Iodine Complex;PVP-I;Poly(vinylpyrrolidone)-Iodine complex;Povidone (iodinated);Poly(vinylpyrrolidone)–Iodine complex;Isodine;Bridine;PVP iodine;Betadine.
CAS No.	25655-41-8
Molecular Formula	C6H9I2NO
Molecular Weight	364.95100
PSA	20.31000
LogP	2.46160

Safety Info

Safety Statements	S24/25
HS Code	3808940010

Properties

Appearance & Physical State	A red-brown crystalline powder
Boiling Point	217.6ºC at 760 mmHg
Melting Point	300ºC
Flash Point	93.9ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in air tight containers.
Vapor Pressure	0.132mmHg at 25°C

Numbering system

MDL number	MFCD00084483
PubChem number	24899316
RTECS number	TR1579600

What is Povidone Iodine?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Povidone Iodine which has developed particularly rapidly in recent years. Do you know about Povidone Iodine?
The official answer: Povidone iodine is an unstable complex of surfactant and iodine, which is a topical disinfectant of the iodoform type. It is a yellowish brown to reddish brown amorphous powder at room temperature, soluble in water or ethanol, insoluble in ether or chloroform. The 1-vinyl-2-arsenyl ketone homopolymer is a surfactant and Chemicalbook contributes to the wetting and penetration of the solution, thus enhancing the bactericidal effect of iodine. It has a high concentration, strong bactericidal power, is tasteless, non-irritating, non-allergenic and has low toxicity. It is a broad-spectrum fungicide, capable of killing viruses, bacteria, budding spores, fungi and protozoa.
Povidone iodine is a loose complex combining elemental iodine and a polymeric carrier, with the povidone acting as a carrier and solubility aid. It is a yellowish brown to brownish red amorphous powder at room temperature. It is slightly odorous, soluble in water or ethanol, acidic in aqueous Chemicalbook, insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride. Povidone iodine aqueous solution has no disadvantages of tincture of iodine, shallow colouring, easy to elute, little irritation to mucous membrane, no need for ethanol deiodination, no corrosive effect and low toxicity.

What’s the application of Povidone Iodine?

The main indications for povidone iodine are as follows: 1. For septic dermatitis, skin fungal infections, small mild burns, also for disinfection of small skin and mucosal wounds. 2. For bacterial and mycotic vaginitis, cervical erosion, trichomonas vaginitis, pubic itching, pubic infections with odour, yellowish smelly leucorrhoea, comprehensive pubic Chemicalbook inflammation, senile vaginitis, herpes, gonorrhoea, syphilis and condyloma acuminatum prevention and local treatment disinfection.3. Glansitis, prepuce, external genitalia and surrounding Prevention and local treatment of gonorrhoea, syphilis, and warts.4. Disinfection of tableware and utensils.5. Disinfection of skin at surgical sites.6.

Conclusion

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