(r)-budesonide CAS# 51372-29-3

(r)-budesonide , Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name: Monopotassium phosphite
CAS No.: 13977-65-6
Molecular Formula: H2KO3P
Molecular weight: 120.09
Sample: Available

(r)-budesonide CAS# 51372-29-3

Description of (r)-budesonide

Dexbudesonide epimer R. Dexbudesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent.

Basic Info of (r)-budesonide

Chemical Name

16a(R),17-(Butylidenebis(oxy))-11b,21-dihydroxypregna-1,4-diene-3,20-dione

Synonyms

arachidonic acid ethanolamide;N-arachidonoylethanolamide;5,8,11,14-Eicosatetraenoylethanolamide;N-Arachidonoyl-2-hydroxyethylamide;N-arachidonoyl ethanolamine;

CAS No.

51372-29-3

Molecular Formula

C25H34O6

Molecular Weight

430.53400

PSA

93.06000

LogP

2.71680

Safety Info

HS Code

2914509090

Properties

Appearance & Physical State

light beige solid

Density

1.27 g/cm3

Boiling Point

599.7ºC at 760 mmHg

Melting Point

194-199ºC

Flash Point

201.8ºC

Storage Condition

-20ºC Freezer

Numbering system

UNII

2HI1006KPH

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What is (r)-budesonide?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Dexbudesonide  which has developed particularly rapidly in recent years. Do you know about Dexbudesonide?

The official answer:Dexbudesonide  is an inhaled glucocorticoid with a strong anti-allergic inflammatory effect, which is weaker than fluticasone propionate and mometasone furoate. The lipid solubility of Dexbudesonide is slightly poorer, but it has a stronger affinity for the glucocorticoid receptor, which is mainly due to the special molecular configuration of Dexbudesonide. Studies have shown that the airway anti-inflammatory strength of Dexbudesonide is 600 times greater than that of hydrocodone and 20-30 times greater than that of dexamethasone, and that inhalation of Dexbudesonide has a strong local effect with less absorption, so that inhalation of a small dose of Dexbudesonide can produce a strong local anti-allergic inflammatory effect in the airway with fewer side effects.

What’s the application of (r)-budesonide?

This product is a glucocorticoid with highly effective local anti-inflammatory effects. It enhances the stability of endothelial cells, smooth muscle cells and lysosomal membranes, inhibits the immune response and reduces antibody synthesis, resulting in a reduction in the release and activity of allergy-active mediators such as histamine, and attenuates the enzymatic process stimulated by antigen-antibody binding to which inhibits the synthesis and release of bronchoconstrictor substances and reduces the contractile response of smooth muscle.

Conclusion

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