Selumetinib CAS 606143-52-6

Selumetinib , Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name: Selumetinib
CAS No.: 606143-52-6
Molecular Fomula: C17H15BrClFN4O3
Molecular weight:457.68
Appearance: Beige powder
Sample: Available

Selumetinib CAS# 606143-52-6

Description of Selumetinib

Selumetinib (AZD6244) is a drug that was discovered by Array BioPharma and was licensed to AstraZeneca. It is being investigated for the treatment of various types of cancer, such as non-small cell lung cancer (NSCLC).

Basic Info of Selumetinib

Chemical Name

Selumetinib

Synonyms

6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide;5-[(4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE;6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide;

CAS No.

606143-52-6

Molecular Formula

C17H15BrClFN4O3

Molecular Weight

457.68100

PSA

88.41000

LogP

3.98950

Safety Info

HS Code

2934999090

Properties

Appearance & Physical State

White or pale white solid.

Density

1.69

Storage Condition

Powder stores in -20ºC directly, which is effective for a period of 2 years.

Numbering system

MDL number

MFCD11977472

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What is Selumetinib?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is CS-1912 which has developed particularly rapidly in recent years. Do you know about CS-1912?

The official answer:CS-1912, chemically known as 5-[(4-bromo-2-chlorophenyl)amino-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide, was developed by AstraZeneca in the UK for the treatment of advanced non-small cell lung cancer (NSCLC). Its therapeutic mechanism is to inhibit the growth of many tumours including B-Raf-mutated melanoma and K-Ras-mutated non-small cell lung cancer (NSCLC) by regulating the levels of MEK, a key protein kinase in the Ras-Raf-MEK-ERK pathway.

What’s the application of Selumetinib?

The anti-cancer drug selumetinib (CS-1912,1) is developed by AstraZeneca in the UK for the treatment of advanced non-small cell lung cancer (NSCLC). CS-1912 inhibits the growth of a number of tumours, including B-Raf-mutated melanoma and K-Ras-mutated non-small cell lung cancer (NSCLC), by regulating levels of MEK, a key protein kinase in the Ras-Raf-MEK-ERK pathway. It is mainly used for the treatment of cholangiocarcinoma, colorectal cancer and NSCLC. Currently, CS-1912 is in phase III clinical trials for the treatment of non-small cell lung cancer.

Conclusion

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Keywords of Selumetinib

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