Sulfamethoxazole CAS 723-46-6
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Chemical Name: Sulfamethoxazole
Sulfamethoxazole: The Complete Guide
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Description of Sulfamethoxazole
SMZ, is an antibiotic. It was used for bacterial infections such as urinary tract infections, bronchitis, and prostatitis and is effective against both gram negative and positive bacteria such as Listeria monocytogenes and E. coli.
Common side effects include nausea, vomiting, loss of appetite, and skin rashes. It is a sulfonamide and bacteriostatic. It resembles a component of folic acid. It prevents folic acid synthesis in the bacteria that must synthesize their own folic acid. Mammalian cells, and some bacteria, do not synthesize but require preformed folic acid (vitamin B9), they are therefore insensitive to sulfamethoxazole.
It was introduced to the United States in 1961. It is now mostly used in combination with trimethoprim (abbreviated SMX-TMP). Other names include: sulfamethalazole, sulfisomezole, and sulfamethazole.
Basic Info of Sulfamethoxazole
P261; P280; P305 + P351 + P338
H315; H317; H319; H335
Appearance & Physical State
Crystals or white powder
482.1ºC at 760 mmHg
Stable, but light sensitive. Incompatible with strong oxidizing agents.
What is Sulfamethoxazole?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is SMZ which has developed particularly rapidly in recent years. Do you know about SMZ?
- The official answer:SMZ, chemically known as 4-amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, is an organic compound with the chemical formula C10H11N3O3S, a white crystalline powder, odourless, slightly bitter in taste, almost insoluble in water, soluble in dilute hydrochloric acid, sodium hydroxide test solution or ammonia test solution. It is mainly used clinically for urinary tract infections, respiratory system infections, intestinal tract infections, biliary tract infections and local soft tissue or wound infections caused by sensitive bacteria.
What’s the application of Sulfamethoxazole?
Particularly effective as an antibacterial agent against Staphylococcus and Escherichia coli. Mainly used for the treatment of avian cholera etc.
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