Tanespimycin CAS 75747-14-7
17-AG , Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name: Tanespimycin
CAS No.:75747-14-7
Molecular Fomula:C31H43N3O8
Molecular weight:585.69
Appearance:solid
Sample: Available

Tanespimycin: The Complete Guide
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Description of Tanespimycin
- 17-AG(17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specific young patients with certain types of leukemia or solid tumors, especially kidney tumors.
- It works by inhibiting Hsp90, which is expressed in those tumors.
It belongs to the family of drugs called antitumor antibiotics.
Basic Info of Tanespimycin
Chemical Name | tanespimycin |
Synonyms | 17-AAG,17AAG;17-AG;17-AGG;17-AAG (Tanespimycin);KOS 953;Expand |
CAS No. | 75747-14-7 |
Molecular Formula | C31H43N3O8 |
Molecular Weight | 585.68800 |
PSA | 166.28000 |
LogP | 3.95760 |
Safety Info
Safety Statements | S22; S24/25; S36; S26 |
WGK Germany | 3 |
Risk Statements | R36/37/38 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | Dark purple solid |
Density | 1.21 |
Boiling Point | 797.8ºC at 760 mmHg |
Melting Point | 201-203ºC |
Flash Point | 436.3ºC |
Refractive Index | 1.566 |
Storage Condition | -20ºC |
Numbering system
UNII | 4GY0AVT3L4 |
What is Tanespimycin?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is 17-AG which has developed particularly rapidly in recent years. Do you know about 17-AG?
- The official answer:17-AG, known in English as Telatinib, has a molecular weight of 585.69 and is a stimulant.
What’s the application of Tanespimycin?
17-AAG is a potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analogue of geldanamycin than geldanamycin. It induces apoptosis in fine Chemicalbook cells and shows antitumour effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt and p185erB2.
Conclusion
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