Triethyl phosphonoacetate CAS 867-13-0

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Chemical Name: Triethyl phosphonoacetate

CAS No.:867-13-0

Molecular Fomula:C8H17O5P

Molecular weight:224.19

Appearance:Clear Liquid

Sample: Available

Triethyl phosphonoacetate CAS#867-13-0

Description of Triethyl phosphonoacetate

tl465 is a reagent for organic synthesis used in the Horner-Wadsworth-Emmons reaction (HWE) or the Horner-Emmons modification.
tl465 can be added dropwise to sodium methoxide solution to prepare a phosphonate ylide. It has an acidic proton that can easily be abstracted by a weak base. When used in an HWE reaction with a carbonyl the resulting alkene formed is usually the E alkene, and is generated with excellent regioselectivity.

Basic Info of Triethyl phosphonoacetate

Chemical Name

Triethyl phosphonoacetate


Diethyl [(ethoxycarbonyl)methyl]phosphonate;

Triethyl phosphonacetate;Triethyl phosphonoac;

Triethyl Phosphonoaceate;(ETHOXYCARBONYLMETHYL)




Molecular Formula


Molecular Weight






Safety Info



Safety Statements


HS Code


WGK Germany



UN 3082

Risk Statements

R36/37/38; R51/53

Hazard Codes



Appearance & Physical State

colorless and light yellow transparent liquid



Boiling Point


Melting Point


Flash Point


Refractive Index



Stable under normal temperatures and pressures.

Storage Condition

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances

Numbering system

MDL number


EINECS number


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What is Triethyl phosphonoacetate?

  • With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. 
  • One such product is tl465 which has developed particularly rapidly in recent years. Do you know about tl465?
  • The official answer:tl465 is a chemical compound with the molecular formula C8H17O5P.

What’s the application of Triethyl phosphonoacetate?

tl465 is an important class of Wittig-horner reagents for intramolecular Heck-type cyclisation reactions and isomerisation reactions in the Horner-Wadsworth-Emmons anti-Chemicalbook reaction, as well as for the manufacture of vitamin compounds, drugs, insect pheromones and other natural compounds.


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United Kingdom Giles
United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
India Shikhar
India Shikhar
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
Korea Kim
Korea Kim
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Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
USA Franklin
USA Franklin
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Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
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Brazil Aline
Brazil Aline
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We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...