Triethyl phosphonoacetate CAS 867-13-0
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Chemical Name: Triethyl phosphonoacetate
CAS No.:867-13-0
Molecular Fomula:C8H17O5P
Molecular weight:224.19
Appearance:Clear Liquid
Sample: Available

Triethyl phosphonoacetate: The Complete Guide
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Description of Triethyl phosphonoacetate
tl465 is a reagent for organic synthesis used in the Horner-Wadsworth-Emmons reaction (HWE) or the Horner-Emmons modification.
tl465 can be added dropwise to sodium methoxide solution to prepare a phosphonate ylide. It has an acidic proton that can easily be abstracted by a weak base. When used in an HWE reaction with a carbonyl the resulting alkene formed is usually the E alkene, and is generated with excellent regioselectivity.
Basic Info of Triethyl phosphonoacetate
Chemical Name | Triethyl phosphonoacetate |
Synonyms | Diethyl [(ethoxycarbonyl)methyl]phosphonate; Triethyl phosphonacetate;Triethyl phosphonoac; Triethyl Phosphonoaceate;(ETHOXYCARBONYLMETHYL) DIETHOXYPHOSPHINEOXIDE;Expand |
CAS No. | 867-13-0 |
Molecular Formula | C8H17O5P |
Molecular Weight | 224.19100 |
PSA | 71.64000 |
LogP | 1.81560 |
Safety Info
RTECS | AG9800000 |
Safety Statements | S26-S37/39-S61 |
HS Code | 2931901990 |
WGK Germany | 3 |
RIDADR | UN 3082 |
Risk Statements | R36/37/38; R51/53 |
Hazard Codes | Xi |
Properties
Appearance & Physical State | colorless and light yellow transparent liquid |
Density | 1.13 |
Boiling Point | 260-262ºC |
Melting Point | -24ºC |
Flash Point | 141.6ºC |
Refractive Index | 1.43-1.432 |
Stability | Stable under normal temperatures and pressures. |
Storage Condition | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances |
Numbering system
MDL number | MFCD00009177 |
EINECS number | 212-757-6 |
What is Triethyl phosphonoacetate?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is tl465 which has developed particularly rapidly in recent years. Do you know about tl465?
- The official answer:tl465 is a chemical compound with the molecular formula C8H17O5P.
What’s the application of Triethyl phosphonoacetate?
tl465 is an important class of Wittig-horner reagents for intramolecular Heck-type cyclisation reactions and isomerisation reactions in the Horner-Wadsworth-Emmons anti-Chemicalbook reaction, as well as for the manufacture of vitamin compounds, drugs, insect pheromones and other natural compounds.
Conclusion
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