Trifluoroacetic acid CAS 76-05-1

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Chemical Name: Trifluoroacetic acid

CAS No.:76-05-1

Molecular Fomula:C2HF3O2

Molecular weight:114.02

Appearance:Colorless Liquid

Sample: Available

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Trifluoroacetic acid CAS#76-05-1

Trifluoroacetic acid: The Complete Guide

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Description of Trifluoroacetic acid

  • CF3COOHis an organofluorine compound with the chemical formula CF3CO2H. It is a colorless liquid with a sharp odor similar to vinegar, but stronger in acidity. TFA is an analogue of acetic acid with the three hydrogen atoms replaced by three fluorine atoms. 
  • The acidity of TFA is approximately 34,000 times stronger than that of acetic acid due to the electronegativity of the trifluoromethyl group. TFA is widely used in organic chemistry for various purposes.

Basic Info of Trifluoroacetic acid

Chemical Name

trifluoroacetic acid

Synonyms

TFA;tri-fluoro-acetic acid;PERFLUOROACETATE;Acetic acid, trifluoro-;TRIFLUOROACETATE;Expand

CAS No.

76-05-1

Molecular Formula

C2HF3O2

Molecular Weight

114.02300

PSA

37.30000

LogP

0.63330

Safety Info

RTECS

AJ9625000

Hazard Class

8

Safety Statements

S26-S27-S28-S45-S61-S9

HS Code

2915900090

WGK Germany

2

Packing Group

I

RIDADR

UN 2699

Risk Statements

R20; R35; R52/53

Hazard Codes

C

Symbol

GHS05, GHS07

Signal Word

Danger

Hazard Declaration

H314; H332; H412

Caution Statement

P261; P273; P280; P303 + P361 + P353; P304 + P340 + P310; P305 + P351 + P338

Properties

Appearance & Physical State

clear liquid

Density

1.535

Boiling Point

72ºC

Melting Point

-15ºC

Flash Point

-3ºC

Refractive Index

1.3

Water Solubility

miscible

Stability

Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases.

Storage Condition

2-8ºC

Vapor Density

3.9 (vs air)

Vapor Pressure

97.5 mm Hg ( 20 °C)

Numbering system

MDL number

MFCD00004169

EINECS number

200-929-3

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What is Trifluoroacetic acid?

  • With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. 
  • One such product is CF3COOH which has developed particularly rapidly in recent years. Do you know about CF3COOH?
  • The official answer:CF3COOH, with the chemical formula CF3COOH and a molecular weight of 114.02, can dissolve proteins if used in combination with carbon disulphide. 
  • It is also an excellent solvent for organic reactions and gives results that are difficult to obtain in normal solvents, e.g. the pyridine ring is preferentially hydrogenated when quinoline is catalyzed in normal solvents, but the benzene ring is preferentially hydrogenated in trifluoroacetic acid.

What’s the application of Trifluoroacetic acid?

It is mainly used in the production of new pesticides, pharmaceuticals and dyestuffs, etc. It also has a large potential for application development in the fields of materials, solvents, etc. Trifluoroacetic acid is mainly used in the synthesis of a variety of herbicides containing trifluoromethyl and heterocyclic Chemicalbook, and can now synthesize a variety of new herbicides with pyridine and quinoline groups; as an extremely strong protonic acid, it is widely used as a catalyst for the alkylation of aromatic compounds, acylation, olefin polymerization and other reactions

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates include more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive systems, Santi-tumor, Nervous systems, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Hello, I’m Pew Ni, the chemical products one-stop solution expert.

Hi, I‘m Peter Ni, the founder of Sincere-Chem, I’ve been running a company in China that exporting chemicals, pharmaceuticals, and intermediates for over 70 countries now. And a range of 50,000 products with the best quality and competitive price to meet your different purchasing needs.

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United Kingdom Giles
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Peter has been my partner for many years, we met at the Shanghai CPHI Fair in 2014, for the first time I didn't have much interest in Peter's products because our company had a stable supplier. Although we didn't work together, Peter would often send me important news and interesting trend information about the industry, so we became good friends, even though I didn't place any orders with him during this time, even if it was a sample order. In September 2016, our original supplier was unable to provide us with the quality and delivery guarantees we needed, so I first thought of Peter and his company. Until now, we have maintained a very good personal friendship in addition to a steady business relationship.
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In all my years of sourcing from China, I first time to found that working with Sincere Chemical was so good, they helped me with all the production and delivery as well as a lot of technical expertise, which saved me a lot of time. When I first approached Peter for a quotation for Optical Brightener, he made me a detailed quotation with not only prices but also foreign trade details, company profile, company strengths, R&D capabilities, production capacity, packaging methods, raw material control, environmental protection, and much more. This information was a very important reference for me in making purchasing decisions. Sincere Chemical is a trustworthy supplier and I believe our business will grow from strength to strength!
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Hi, I'm Kim, I'm Peter's partner and although I don't like him very much (because he never gives me more money for my prices, hahaha) I'm still willing to write him customer feedback. As an international buyer, I have to deal with a lot of things every day and my inbox is often full of development letters. It's a lot of junk and meaningless pleasantries, which I don't like that much, but Peter's emails always give me a better understanding of the product and the industry. I am also very pleased with his work ethic, and I am very happy with his work every time I work with him, not only in providing quotations but also in facilitating all the details of my work so that I can concentrate more on other things, so he is the best supplier for me. Although his prices are not the lowest among all suppliers, his products give me the greatest peace of mind.
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Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other.
Canada Kate
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I just got the product. The quality is awesome. I’m very happy. Hope to place soon a new order in your company. Also wish for our future business.
Unilever
Unilever
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Sincere Chemical is a reliable and professional company. Not only on exporting but also their professional team service. Their team gave us so many suggestions for our new project. We are really satisfied with their awesome service and best product quality. Sincere-Chem’s vendor code is 51465768 in our cooperated vendor list system.
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I have visited Sincere Chemical company in the year 2018. Their company can be considered as one of the most professional, customer-focused, and product quality-driven companies that I have worked with in recent years.
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We are a pharmaceutical products manufacturer in Brazil. I’m happy to cooperate with Sincere Chemical especially cooperate with Peter. Peter is patient and friendly. I’m satisfied with his 24*7 hours service. We are not only cooperators but also best friends with each other.
Mexico Gonzalo
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Great service and very supportive. This is my first order and I feel fortunate to be with Peter and his company. Product received was the right good quality product, so my review is more related with the quality, service and shipment. Thank you for sending. next time I will order again. Good supplier...
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