Valsartan CAS# 137862-53-4
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Chemical Name: Valsartan
CAS No.: 137862-53-4
Molecular Formula C24H29N5O3
Average mass 435.519
Appearance: white crystalline powder
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Description of Valsartan
Valsartan (trade name Diovan) is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for the type I (AT1) angiotensin receptor. Valsartan is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.
Basic Info of Valsartan
Appearance & Physical State
white crystalline powder
684.9ºC at 760 mmHg
Store in original container in a cool dark place.
1.06E-19mmHg at 25°C
What is Valsartan?
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The official answer: Valsartan is an angiotensin II receptor antagonist anti-hypertensive drug that acts to close the type I (AT1) receptor of angiotensin II, increase angiotensin II plasma levels, stimulate unclosed AT2 receptors, and counteract the effects of AT1 receptors, thereby achieving vasodilatation and lowering blood pressure. In the United States, valsartan is a drug used to treat hypertension, congestive heart failure, and post-myocardial infarction. Valsartan was first marketed in Germany in July 1996, and has since been marketed in Europe, the United States and Japan. Vaporba-Gage and Sandoz merged in 1996 to form Novartis. Valsartan has a long-lasting and stable blood pressure lowering effect and low toxic side effects.
What’s the application of Valsartan?
Uses Anti-hypertensive drug. Non-peptide angiotensin II AT1-receptor antagonist. Used for the treatment of hypertension.
Valsartan (Valsartan) is a used anti-hypertensive drug in clinical practice, with the advantages of low side effects and good tolerability, and can also be used for the treatment of hypertension in patients with diabetes and renal disease.
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